Biologics Versus JAK Inhibitors. Part II: Risk of Infections. A Narrative Review

M Mansilla-Polo, D Morgado-Carrasco - Dermatology and Therapy, 2024 - Springer
Introduction The risk of infections associated with biological drugs (BD) and Janus kinase
inhibitors (JAKi) has been extensively explored in the literature. However, there is a dearth …

Risk of infection in patients with inflammatory bowel disease treated with interleukin-targeting agents: a systematic review and meta-analysis

K Ouranos, H Saleem, S Vassilopoulos… - Inflammatory bowel …, 2025 - academic.oup.com
Background Patients with inflammatory bowel disease (IBD) are at increased risk of
infection. The aim of this study was to assess the cumulative incidence and risk of infection …

Anti‐TNF therapy impairs both short‐and long‐term IgG responses after repeated vaccination

JS Buhre, T Pongracz, UM Geisen, M Schubert… - Allergy, 2024 - Wiley Online Library
Background Recently, it has been questioned whether vaccination of patients with
inflammatory (auto) immune diseases under anti‐tumor necrosis factor (TNF) treatment …

Incidence of New-Onset Inflammatory Bowel Disease, Oral and Gastrointestinal Candidiasis, Herpes Zoster, Pulmonary Tuberculosis, and Major Cardiovascular …

DH Kang, BL Lew, SH Kwon - Journal of Clinical Medicine, 2023 - mdpi.com
The multicenter, retrospective cohort study was aimed at examining adverse events in
biologic-treated patients with moderate-to-severe psoriasis by using a real-world database …

Prevalence of pretreatment testing recommended for patients with chronic inflammatory skin diseases

MC Schneeweiss, D Shay, S Ly, R Wyss… - JAMA …, 2024 - jamanetwork.com
Importance Laboratory testing for the presence of tuberculosis, hepatitis, and other
conditions before starting most systemic immunomodulatory agents is recommended in …

Vitiligo is associated with an increased risk of cardiovascular diseases: a large-scale, propensity-matched, US-based retrospective study

A Frączek, A Owczarczyk-Saczonek, RJ Ludwig… - Ebiomedicine, 2024 - thelancet.com
Background Vitiligo is an autoimmune disease, characterized by specific destruction of
melanocytes. While associations with numerous comorbid conditions, which potentially …

Effectiveness and safety of biological therapies in very severe plaque psoriasis: a real-life retrospective study

G Fiorillo, L Ibba, L Gargiulo, A Narcisi… - Journal of Personalized …, 2024 - mdpi.com
Psoriasis can have a significant impact on quality of life and productivity, especially with
increased severity. However, there is limited evidence on biologics' efficacy in highly severe …

Interleukin inhibitors and the associated risk of candidiasis

S Khan, H Bilal, MN Khan, W Fang, W Chang… - Frontiers in …, 2024 - frontiersin.org
Interleukins (ILs) are vital in regulating the immune system, enabling to combat fungal
diseases like candidiasis effectively. Their inhibition may cause enhanced susceptibility to …

Clinical Data on Laboratory Testing for Patients Taking Systemic Immunomodulatory Agents: Do We Order Them Enough or Too Much?

CW Enos, AO Vera, AS Van Voorhees - JAMA dermatology, 2024 - jamanetwork.com
In this issue of JAMA Dermatology, Schneeweiss et al1 present an article examining
laboratory screening and monitoring patterns in treating patients with chronic inflammatory …

Psoriasis Flare Following Paramyxovirus Infection

V Di Lernia, C Bertoli - Psoriasis: Targets and Therapy, 2024 - Taylor & Francis
Psoriasis is a chronic, immunologically mediated disease of multifactorial origin, with genes
playing a key role and environmental factors, such as infections, often triggering its onset or …