Cystic fibrosis (CF) is a lethal genetic disease caused by mutations in the chloride ion
channel cystic fibrosis transmembrane conductance regulator (CFTR). Class-II mutants of …

Cystic fibrosis (CF) is a fatal autosomal recessive disorder caused by the loss of function
mutations within a single gene for the Cystic Fibrosis Transmembrane Conductance …

Cystic fibrosis (CF) is caused by mutations that compromise the expression and/or function
of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. Most …

Cystic fibrosis (CF) is one of the most prevalent lethal genetic diseases with over 2000
identified mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) …

The most prevalent cystic fibrosis (CF)-causing mutation–F508del–impairs the folding of
CFTR protein, resulting in its defective trafficking and premature degradation. Small …

An Italian, 46-year-old female patient carrying the complex allele p.[R74W; V201M; D1270N]
in trans with CFTR dele22_24 was diagnosed at the Cystic Fibrosis (CF) Center of Verona …

Most of the 2,100 CFTR gene variants reported to date are still unknown in terms of their
disease liability in Cystic Fibrosis (CF) and their molecular and cellular mechanism that …

Cystic Fibrosis (CF) is a genetic disease caused by mutations in the gene encoding the
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) channel. Currently, more …

Mutation targeted therapy in cystic fibrosis (CF) is still not eligible for all CF subjects,
especially for cases carrying rare variants such as the CFTR genotype W57G/A234D (c …

Cystic fibrosis is a genetic disorder caused by a Cystic Fibrosis Transmembrane
Conductance Regulator (CFTR) gene defect. Many across the globe suffer the debilitating …