Abnormal Cerebrovascular Activity, Perfusion, and Glymphatic Clearance in Lewy Body Diseases

SG Ryman, AA Vakhtin, AR Mayer… - Movement …, 2024 - Wiley Online Library
Cerebrovascular activity is not only crucial to optimal cerebral perfusion, but also plays an
important role in the glymphatic clearance of interstitial waste, including α‐synuclein. This …

[HTML][HTML] The circadian rhythm: A new target of natural products that can protect against diseases of the metabolic system, cardiovascular system, and nervous system

M Xin, F Bi, C Wang, Y Huang, Y Xu, S Liang… - Journal of Advanced …, 2024 - Elsevier
Background The treatment of metabolic system, cardiovascular system, and nervous system
diseases remains to be explored. In the internal environment of organisms, the metabolism …

CO2 as an engine for neurofluid flow: Exploring the coupling between vascular reactivity, brain clearance, and changes in tissue properties

EC van Der Voort, Y Tong, EE van Grinsven… - NMR in …, 2024 - Wiley Online Library
The brain relies on an effective clearance mechanism to remove metabolic waste products
for the maintenance of homeostasis. Recent studies have focused on elucidating the forces …

Using Respiratory Challenges to modulate CSF movement across different physiological pathways–An fMRI Study

VV Nair, TC Diorio, Q Wen, VL Rayz, Y Tong - Imaging Neuroscience, 2024 - direct.mit.edu
With growing evidence signifying the impact of cerebrospinal fluid (CSF) flow in facilitating
waste clearance from the brain and potential pathophysiological links to neurodegenerative …

Sleep, Glial Function, and the Endocannabinoid System: Implications for Neuroinflammation and Sleep Disorders

J Camberos-Barraza, A Camacho-Zamora… - International Journal of …, 2024 - mdpi.com
The relationship between sleep, glial cells, and the endocannabinoid system represents a
multifaceted regulatory network with profound implications for neuroinflammation and …

Cardiovascular responses to natural and auditory evoked slow waves predict post-sleep cardiac function

G Alessandrelli, S Huwiler, G Bernardi… - bioRxiv, 2024 - biorxiv.org
The interplay between slow-wave sleep and cardiovascular health is increasingly
recognized. Our prior research showed that auditory-enhanced slow waves can boost …

Sleep-Induced Vasomotor Pulsation is a Driver of Cerebrospinal Fluid and Blood-Brain Barrier Dynamics in the Human Brain

T Vä yrynen, J Tuunanen, H Helakari, V Korhonen… - bioRxiv, 2024 - biorxiv.org
Sleep is crucial for restoring and maintaining brain tissue homeostasis, primarily through
enhanced transport of cerebrospinal fluid (CSF) solutes. Infra-slow (< 0.1 Hz) vasomotion …

Cholinergic basal forebrain neurons regulate vascular dynamics and cerebrospinal fluid flux

KH Chuang, XA Zhou, Y Xia, Z Li, L Qian, E Eeles… - bioRxiv, 2024 - biorxiv.org
Waste from the brain is cleared via a cerebrospinal fluid (CSF) exchange pathway, the
dysfunction of which is suggested to underlie the pathogenesis of many brain conditions …

HUMAN CEREBROSPINAL FLUID MOVEMENT ACROSS WAKE AND SLEEP STATES–A MULTIMODAL IMAGING STUDY

VV Nair - 2024 - hammer.purdue.edu
The movement of Cerebrospinal Fluid (CSF) within the brain's ventricles and the
subarachnoid spaces of both the cranium and spine is crucial for the health and functioning …

NREM3 sleep disrupts the brain-periphery hemodynamic coupling

VV Nair, BR Kish, H Oshima, Q Wen… - Optics in Health …, 2024 - spiedigitallibrary.org
This study investigates the coupling strength between low-frequency peripheral and
cerebral hemodynamics among young, healthy volunteers, with concurrent acquisition of …