Allogeneic stem cell transplantation (allo-SCT) is a curable method for the treatment of
hematological malignancies. In the past two decades, the establishment of haploidentical …

Inhibition of the mechanistic target of rapamycin (mTOR) has been exploited largely both in
solid tumour oncology and solid organ transplantation. More recently mTOR inhibitors such …

The presence of donor-specific antibodies (DSA) are associated with graft failure either
following human leukocyte antigen (HLA)-mismatched allogeneic stem cell transplantation …

There is evidence of continuous bidirectional cross-talk between malignant cells and bone
marrow-derived mesenchymal stromal cells (BM-MSC), which favors the emergence and …

The use of reduced-intensity conditioning (RIC) regimens has decreased the risk of
nonrelapse mortality (NRM) after allogeneic stem cell transplantation (alloSCT). In contrast …

The immunosuppressant rapamycin (RAPA) inhibits mammalian target of rapamycin
(mTOR) functions and is applied after allogeneic bone marrow transplantation (BMT) to …

Cystic echinococcosis (CE) is a worldwide distributed helminthic zoonosis caused by
Echinococcus granulosus. Benzimidazole derivatives are currently the only drugs for …

Because of the toxicity associated with myeloablative conditioning, nonmyeloablative
regimens are increasingly being used in vulnerable patient populations. For patients with …

Highlights•Bortezomib posses a number of immunomodulatory effects that span a wide
range of cellular processes of T and dendritic cells.•Murine and early clinical studies suggest …

In this study, we aimed to modify the immune response in the long term after allogeneic
bone marrow transplantation (allo-BMT) by using the proteasome inhibitor ixazomib (IXZ) at …