[HTML][HTML] Small heat shock proteins: role in cellular functions and pathology

R Bakthisaran, R Tangirala, CM Rao - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
Small heat shock proteins (sHsps) are conserved across species and are important in stress
tolerance. Many sHsps exhibit chaperone-like activity in preventing aggregation of target …

Apoptosis, autophagy and atherosclerosis: relationships and the role of Hsp27

R Shan, N Liu, Y Yan, B Liu - Pharmacological research, 2021 - Elsevier
Atherosclerosis is a multifactorial chronic inflammatory disease of the arterial wall, and an
important pathological basis of coronary heart disease. Endothelial cells, vascular smooth …

[HTML][HTML] The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via …

ER Gallagher, ELF Holzbaur - Cell reports, 2023 - cell.com
In response to lysosomal damage, cells engage several quality-control mechanisms,
including the selective isolation and degradation of damaged lysosomes by lysophagy …

Understanding postmortem biochemical processes and post-harvest aging factors to develop novel smart-aging strategies

YHB Kim, D Ma, D Setyabrata, MM Farouk… - Meat Science, 2018 - Elsevier
Postmortem aging is a value-adding process and has been extensively practiced by the
global meat industry for years. The rate and extent of aging impacts on meat quality …

HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy

X Wang, M Chen, J Zhou… - … journal of oncology, 2014 - spandidos-publications.com
Among the heat shock proteins (HSP), HSP27, HSP70 and HSP90 are the most studied
stress-inducible HSPs, and are induced in response to a wide variety of physiological and …

Roles of heat shock factor 1 beyond the heat shock response

J Barna, P Csermely, T Vellai - Cellular and Molecular Life Sciences, 2018 - Springer
Various stress factors leading to protein damage induce the activation of an evolutionarily
conserved cell protective mechanism, the heat shock response (HSR), to maintain protein …

Heat shock proteins: essential proteins for apoptosis regulation

D Lanneau, M Brunet, E Frisan, E Solary… - Journal of cellular …, 2008 - Wiley Online Library
Introduction• Main HSPs• HSPs, cell signalling and apoptosis‐HSPs' targets in upstream
signalling pathways‐HSPs' targets at the mitochondrial level‐HSPs' targets at the post …

Biotherapeutic-loaded injectable hydrogels as a synergistic strategy to support myocardial repair after myocardial infarction

Z Zheng, Y Tan, Y Li, Y Liu, G Yi, CY Yu… - Journal of Controlled …, 2021 - Elsevier
Myocardial infarction (MI) has been considered as the leading cause of cardiovascular-
related deaths worldwide. Although traditional therapeutic agents including various …

Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death

A Parihar, TD Eubank, AI Doseff - Journal of innate immunity, 2010 - karger.com
Monocytes and macrophages are central cells of the innate immune system, responsible for
defending against diverse pathogens. While they originate from a common myeloid …

Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death

J Acunzo, M Katsogiannou, P Rocchi - … journal of biochemistry & cell biology, 2012 - Elsevier
Hsp27, αB-crystallin and HSP22 are ubiquitous small heat shock proteins (sHsp) whose
expression is induced in response to a wide variety of unfavorable physiological and …