Lithium increases platelet serine-9 phosphorylated GSK-3β levels in drug-free bipolar disorder during depressive episodes
Background Glycogen synthase kinase-3 β (GSK3β) is an intracellular enzyme directly
implicated in several neural processes relevant to bipolar disorder (BD) pathophysiology …
implicated in several neural processes relevant to bipolar disorder (BD) pathophysiology …
Low platelet iPLA2 activity predicts conversion from mild cognitive impairment to Alzheimer's disease: a 4-year follow-up study
Abstract Reduced phospholipase A 2 (PLA 2) activity has been reported in the brain and in
blood cells of patients with Alzheimer's disease (AD). Individuals with mild cognitive …
blood cells of patients with Alzheimer's disease (AD). Individuals with mild cognitive …
Cognitive stimulation modulates platelet total phospholipases a 2 activity in subjects with mild cognitive impairment
We evaluated the effect of cognitive stimulation (CS) on platelet total phospholipases A 2
activity (tPLA 2 A) in patients with mild cognitive impairment (MCI_P). At baseline, tPLA 2 A …
activity (tPLA 2 A) in patients with mild cognitive impairment (MCI_P). At baseline, tPLA 2 A …
Polyunsaturated fatty acid biostatus, phospholipase A2 activity and brain white matter microstructure across adolescence
RK McNamara, PR Szeszko, S Smesny, T Ikuta… - Neuroscience, 2017 - Elsevier
Adolescence is a period of major brain white matter (WM) changes, and membrane lipid
metabolism likely plays a critical role in brain WM myelination. Long-chain polyunsaturated …
metabolism likely plays a critical role in brain WM myelination. Long-chain polyunsaturated …
Reduced activities of phospholipases A2 in platelets of drug‐naïve bipolar disorder patients
EH Ikenaga, LL Talib, AS Ferreira… - Bipolar …, 2015 - Wiley Online Library
Objective Phospholipases A2 (PLA2) comprise a family of hydrolytic enzymes that cleave
membrane phospholipids and play a key role in cellular homeostasis. Alterations in …
membrane phospholipids and play a key role in cellular homeostasis. Alterations in …
Some cross-talks between immune cells and epilepsy should not be forgotten
H Wang, S Liu, Z Tang, J Liu - Neurological Sciences, 2014 - Springer
Recent studies have reported that immune cells were not always found in brain specimens
from epileptic patients, then should we stop investigating the relationship between these …
from epileptic patients, then should we stop investigating the relationship between these …