Effects of mesenchymal stem cell-derived exosomes on autoimmune diseases

Z Shen, W Huang, J Liu, J Tian, S Wang… - Frontiers in …, 2021 - frontiersin.org
Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …

Mesenchymal stromal cell therapies: immunomodulatory properties and clinical progress

X Wu, J Jiang, Z Gu, J Zhang, Y Chen, X Liu - Stem cell research & …, 2020 - Springer
Mesenchymal stromal cells (MSCs) are a subset of heterogeneous non-hematopoietic
fibroblast-like cells that can differentiate into cells of multiple lineages, such as …

Mesenchymal stem cell immunomodulation: mechanisms and therapeutic potential

N Song, M Scholtemeijer, K Shah - Trends in pharmacological sciences, 2020 - cell.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells that are emerging as the most
promising means of allogeneic cell therapy. MSCs have inherent immunomodulatory …

Mesenchymal stem cell-derived secretome: a potential therapeutic option for autoimmune and immune-mediated inflammatory diseases

G Műzes, F Sipos - Cells, 2022 - mdpi.com
Immune-mediated inflammatory diseases (IMIDs) encompass several entities such as
“classic” autoimmune disorders or immune-mediated diseases with autoinflammatory …

Biology and therapeutic potential of mesenchymal stem cell‐derived exosomes

Z Xunian, R Kalluri - Cancer Science, 2020 - Wiley Online Library
Mesenchymal stem cells (MSC) are multipotent stromal cells with the potential to
differentiate into several cell types. MSC‐based therapy has emerged as a promising …

Insights into the secretome of mesenchymal stem cells and its potential applications

S Eleuteri, A Fierabracci - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) have regenerative, immunoregulatory properties and can
be easily isolated and expanded in vitro. Despite being a powerful tool for clinical …

The immunomodulatory functions of mesenchymal stromal/stem cells mediated via paracrine activity

Y Zhou, Y Yamamoto, Z Xiao, T Ochiya - Journal of clinical medicine, 2019 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) exist in almost all tissues, possessing the potential
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …

Exosomal microRNAs derived from mesenchymal stem cells: cell-to-cell messages

K Asgarpour, Z Shojaei, F Amiri, J Ai… - Cell Communication and …, 2020 - Springer
Exosomes are extracellular vesicles characterized by their size, source, release mechanism
and contents. MicroRNAs (miRNAs) are single stranded non-coding RNAs transcribed from …

[HTML][HTML] Mesenchymal stromal/stem cell-derived extracellular vesicles in tissue repair: challenges and opportunities

S Varderidou-Minasian, MJ Lorenowicz - Theranostics, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem/stromal cells (MSCs) are important players in tissue homeostasis and
regeneration owing to their immunomodulatory potential and release of trophic factors that …

[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine

M Li, F Fang, M Sun, Y Zhang, M Hu, J Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …