Inherent safety concept based proactive risk reduction strategies: A review

W Pu, AAA Raman, MD Hamid, X Gao… - Journal of Loss …, 2023 - Elsevier
The growing scale and complexity of process industries have brought safety, health, and
environmental issues to the forefront. As a result, proactive risk reduction strategies (RRSs) …

Review on the Inherently Safer Design for chemical processes: Past, present and future

X Gao, AAA Raman, HF Hizaddin, MM Bello… - Journal of Cleaner …, 2021 - Elsevier
Since the inception of inherent safety in the 1970s, impressive progress has been made in
using it to shape Friendlier Chemical Processes (FCP) which are largely characterized by …

Thermal stability assessment of peptide coupling reagents commonly used in pharmaceutical manufacturing

JB Sperry, CJ Minteer, JY Tao, R Johnson… - … Process Research & …, 2018 - ACS Publications
Amide couplings are one of, if not the most common chemical reactions performed in the
pharmaceutical industry. Many amide bonds are generated with the help of highly active …

Development of a general inherent safety assessment tool at early design stage of chemical process

J Zhu, Z Liu, Z Cao, X Han, L Hao, H Wei - Process Safety and …, 2022 - Elsevier
The purpose of process safety is the prevention and mitigation of incidents arising from
process-related hazards while inherent safety design is one of the most effective ways to …

Systematic review on the implementation methodologies of inherent safety in chemical process

X Gao, AAA Raman, HF Hizaddin, MM Bello - Journal of Loss Prevention in …, 2020 - Elsevier
The accomplishments of inherent safety in the field of loss prevention thus far are impressive
due to its scientific philosophy: reducing risks at source rather than adding engineered and …

A review of inherent assessment for sustainable process design

M Athar, AM Shariff, A Buang - Journal of cleaner production, 2019 - Elsevier
Chemical process manufacturing is associated with risks, which cannot be eliminated.
Anyhow, controlling or minimizing of risks is possible up to a certain extent through various …

Methodology for selection of inherently safer process design alternatives based on safety indices

J Janošovský, I Rosa, G Vincent, B Šulgan… - Process Safety and …, 2022 - Elsevier
Safety is a key part of any modern production process and as such is reflected in legislation
and work regulations. Decision-making concept based on inherently safer design principles …

Why major accidents are still occurring

PR Amyotte, S Berger, DW Edwards, JP Gupta… - Current opinion in …, 2016 - Elsevier
Highlights•Offers an examination of major process accident causes.•Focus is on lessons
from Bhopal tragedy.•These lessons must not be forgotten.Major accidents happen in the …

Inherent Process Risk Index (IPRI)–A tool for analyzing inherently safer design using Aspen Plus simulation

Y Qian, S Vaddiraju, F Khan - Process Safety and Environmental Protection, 2024 - Elsevier
The rapid expansion of the chemical process industry necessitates an increased emphasis
on process safety. Inherently safer design strategies are one of the most reliable and robust …

Including inherent safety in the design of chemical processes

AP Ortiz-Espinoza, A Jiménez-Gutiérrez… - Industrial & …, 2017 - ACS Publications
Past industrial accidents have raised major concern for the inclusion of safety as part of the
design of a chemical process, an item typically carried out after the process design has been …