Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …

To date, thousands of highly abundant and conserved single-stranded RNA molecules
shaped into ring structures (circRNAs) have been identified. CircRNAs are multifunctional …

Long noncoding RNAs (lncRNAs) are sequences of 200 nucleotides or more that are
transcribed from a large portion of the mammalian genome. While hypothesized to have a …

Circular (circ) RNAs have emerged as novel regulators of gene expression through various
mechanisms. However, most publications focus on functional circRNAs regulating target …

The accelerated progress and approval of two mRNA-based vaccines to address the SARS-
CoV-2 virus were unprecedented. This record-setting feat was made possible through the …

Over the past decade, circular RNA (circRNA) research has evolved into a bona fide
research field shedding light on the functional consequence of this unique family of RNA …

Tumor microenvironment (TME) is a crucial regulator of tumor progression and cells in the
TME release a number of molecules that are responsible for anaplasticity, invasion …

Messenger RNA (mRNA)‐based therapy has emerged as a powerful, safe, and rapidly
scalable therapeutic approach that involves technologies for both mRNA itself and the …

Circular RNAs are an unusual class of single-stranded RNAs whose ends are covalently
linked via back-splicing. Due to their versatility, the need to express circular RNAs in vivo …

Numerous circular RNAs (circRNAs) produced from back-splicing of exon (s) have been
recently revealed on a genome-wide scale across species. Although generally expressed at …