Reactive Oxygen Species and Oxidative Stress in Vascular‐Related Diseases

XM Cheng, YY Hu, T Yang, N Wu… - Oxidative Medicine and …, 2022 - Wiley Online Library
Oxidative stress (OS) refers to the enhancement of oxidation and the decreased of related
antioxidant enzymes activity under pathological conditions, resulting in relatively excess …

Sirt3 protects against thoracic aortic dissection formation by reducing reactive oxygen species, vascular inflammation, and apoptosis of smooth muscle cells

L Qiu, S Yi, T Yu, Y Hao - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Sirtuin3 (Sirt3) is a histone deacetylase involved in the regulation of many cellular
processes. Sirt3 deficiency is known to increase oxidative stress. Reactive oxygen species …

Second heart field–derived cells contribute to angiotensin II–mediated ascending aortopathies

H Sawada, Y Katsumata, H Higashi, C Zhang, Y Li… - Circulation, 2022 - Am Heart Assoc
Background: The ascending aorta is a common location for aneurysm and dissection. This
aortic region is populated by a mosaic of medial and adventitial cells that are embryonically …

Mangiferin Inhibits PDGF‐BB‐Induced Proliferation and Migration of Rat Vascular Smooth Muscle Cells and Alleviates Neointimal Formation in Mice through the …

Q Wu, Y Chen, Z Wang, X Cai, Y Che… - Oxidative Medicine …, 2021 - Wiley Online Library
Mangiferin is a naturally occurring xanthone C‐glycoside that is widely found in various
plants. Previous studies have reported that mangiferin inhibits tumor cell proliferation and …

[HTML][HTML] Amarogentin inhibits vascular smooth muscle cell proliferation and migration and attenuates neointimal hyperplasia via AMPK activation

F Jia, R Ji, G Qiao, Z Sun, X Chen, Z Zhang - Biochimica et Biophysica Acta …, 2023 - Elsevier
Objectives Recent studies validated the expression of extraoral bitter taste receptors and
established the importance of regulatory functions that are associated with various cellular …

IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis

W Ren, Z Wang, J Wang, Z Wu, Q Ren, A Yu, Y Ruan - Life sciences, 2020 - Elsevier
Background As an inflammation-related cytokine, interleukin (IL)-5 has been reported to be
involved in the development of cardiovascular diseases, such as chronic heart failure and …

Prediction of the Mechanism of Sodium Butyrate against Radiation-Induced Lung Injury in Non-Small Cell Lung Cancer Based on Network Pharmacology and …

X Zhang, M Chen, P Fan, T Su, S Liang… - Frontiers in …, 2022 - frontiersin.org
Background Radiation-induced lung injury (RILI) is a severe side effect of radiotherapy for
non-small cell lung cancer (NSCLC), and one of the major hindrances to improve the …

BOP1 knockdown attenuates neointimal hyperplasia by activating p53 and inhibiting nascent protein synthesis

F Jia, Q Wu, Z Wang, M Zhang, S Yuan… - Oxidative medicine …, 2021 - Wiley Online Library
The rate of ribosome biogenesis plays a vital role in cell cycle progression and proliferation
and is strongly connected with coronary restenosis and atherosclerosis. Blocking of …

Identification of key differentially methylated genes in regulating muscle development and intramuscular fat deposition in chickens

B Yu, Z Cai, J Liu, T Zhang, X Feng, C Wang, J Li… - International Journal of …, 2024 - Elsevier
Muscle development and intramuscular fat (IMF) deposition are intricate physiological
processes characterized by multiple gene expressions and interactions. In this research, the …

Glut10 restrains neointima formation by promoting SMCs mtDNA demethylation and improving mitochondrial function

Q Wu, Z Hu, Z Wang, Y Che, M Zhang, S Zheng… - Translational …, 2023 - Elsevier
Neointimal hyperplasia is a major clinical complication of coronary artery bypass graft and
percutaneous coronary intervention. Smooth muscle cells (SMCs) play a vital roles in …