Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance …

Discoveries have emerged highlighting the complex nature of the interorgan cross-talk
between the kidney and the lung. Vascular rigidity, neurohormonal activation, tissue …

Background Multi-organ dysfunction in critical illness is common and frequently involves the
lungs and kidneys, often requiring organ support such as invasive mechanical ventilation …

Background: High-output heart failure (HF) is an unusual cause of cardiac failure that has
not been well-characterized. Objectives: This study sought to characterize the etiologies …

Mild-to-moderate pulmonary hypertension is a common complication of chronic obstructive
pulmonary disease (COPD); such a complication is associated with increased risks of …

Aims Very few data exist on the occurrence of acute kidney injury (AKI) associated with
transcatheter aortic valve implantation (TAVI). The objectives of the present study were (i) to …

Over the past decade, science has greatly advanced our understanding of interdependent
feedback mechanisms involving the heart, lung, and kidney. Organ injury is the …

Recognition of heart failure (HF) may be difficult in patients presenting with acute dyspnoea,
particularly in the presence of chronic airways obstruction. Since increased secretion of the …

Thirty to fifty percent of patients presenting with signs and symptoms of heart failure have a
normal left ventricular (LV) systolic ejection fraction. The clinical examination cannot …

BACKGROUND--Patients with chronic severe anaemia often retain salt and water. Fluid
retention in these patients is not caused by heart failure and the exact mechanisms remain …