Abstract Purpose of Review Cardiovascular diseases are the leading cause of death
worldwide, largely due to the limited regenerative capacity of the adult human heart. In …

Cardiovascular disease is the leading cause of death worldwide. Advanced insights into
disease mechanisms and therapeutic strategies require a deeper understanding of the …

Myocardial infarction (MI) is one of the most serious health threats, resulting in huge physical
and economic burdens worldwide. Wnt signaling pathways play an important role in …

The blueprints of developing organs are preset at the early stages of embryogenesis.
Transcriptional and epigenetic mechanisms are proposed to preset developmental …

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are promising
candidates to treat myocardial infarction and other cardiac diseases. Such treatments …

WNT5B, a member of the WNT family of proteins that is closely related to WNT5A, is required
for cell migration, cell proliferation, or cell differentiation in many cell types. WNT5B signals …

Wnt signaling occurs through evolutionarily conserved pathways that affect cellular
proliferation and fate decisions during development and tissue maintenance. Alterations in …

During embryo development, cell proliferation, cell fate specification and tissue patterning
are coordinated and tightly regulated by a handful of evolutionarily conserved signaling …

Although it is widely accepted that better food habits do play important role in cancer
prevention and treatment, how dietary agents mediate their effects remains poorly …

Silicosis is a chronic pulmonary disease characterized by diffuse fibrosis of lung caused by
the deposition of silica dust (SiO 2). The inhaled silica-induced oxidative stress, ROS …