Unveiling the connection: long-chain non-coding RNAs and critical signaling pathways in breast cancer
Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways
essential for cell proliferation, survival, and differentiation. Recently, the significant …
essential for cell proliferation, survival, and differentiation. Recently, the significant …
[HTML][HTML] The m6A RNA methylation regulates oncogenic signaling pathways driving cell malignant transformation and carcinogenesis
The m 6 A RNA methylation is the most prevalent internal modification in mammalian
mRNAs which plays critical biological roles by regulating vital cellular processes …
mRNAs which plays critical biological roles by regulating vital cellular processes …
[HTML][HTML] m6A regulator-based methylation modification patterns characterized by distinct tumor microenvironment immune profiles in colon cancer
W Chong, L Shang, J Liu, Z Fang, F Du, H Wu, Y Liu… - Theranostics, 2021 - ncbi.nlm.nih.gov
Recent studies have highlighted the biological significance of RNA N 6-methyladenosine (m
6 A) modification in tumorigenicity and progression. However, it remains unclear whether m …
6 A) modification in tumorigenicity and progression. However, it remains unclear whether m …
[HTML][HTML] The evolving landscape of N6-methyladenosine modification in the tumor microenvironment
Y Gu, X Wu, J Zhang, Y Fang, Y Pan, Y Shu, P Ma - Molecular Therapy, 2021 - cell.com
The tumor microenvironment (TME), controlled by intrinsic mechanisms of carcinogenesis
and epigenetic modifications, has, in recent years, become a heavily researched topic. The …
and epigenetic modifications, has, in recent years, become a heavily researched topic. The …
[HTML][HTML] Prognostic significance and tumor immune microenvironment heterogenicity of m5C RNA methylation regulators in triple-negative breast cancer
Z Huang, J Pan, H Wang, X Du, Y Xu… - Frontiers in cell and …, 2021 - frontiersin.org
Purpose The m5C RNA methylation regulators are closely related to tumor proliferation,
occurrence, and metastasis. This study aimed to investigate the gene expression …
occurrence, and metastasis. This study aimed to investigate the gene expression …
[HTML][HTML] Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma
C Zhang, L Chen, Y Liu, J Huang, A Liu, Y Xu… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Methyltransferase-like 14 (METTL14) participates in tumorigenesis in several
malignancies, but how METTL14 mediates the metastasis of renal cell carcinoma (RCC) has …
malignancies, but how METTL14 mediates the metastasis of renal cell carcinoma (RCC) has …
[HTML][HTML] Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m6A signaling
K Sun, Y Du, Y Hou, M Zhao, J Li, Y Du, L Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Purpose: The implementation of targeted therapies for acute myeloid leukemia (AML) has
been challenging. Fat mass and obesity associated protein (FTO), an mRNA N 6 …
been challenging. Fat mass and obesity associated protein (FTO), an mRNA N 6 …
[HTML][HTML] A functional loop between YTH domain family protein YTHDF3 mediated m6A modification and phosphofructokinase PFKL in glycolysis of hepatocellular …
R Zhou, W Ni, C Qin, Y Zhou, Y Li, J Huo, L Bian… - Journal of Experimental …, 2022 - Springer
Abstract Background & aims N6-methyladenosine (m6A) modification plays a critical role in
progression of hepatocellular carcinoma (HCC), and aerobic glycolysis is a hallmark of …
progression of hepatocellular carcinoma (HCC), and aerobic glycolysis is a hallmark of …
Role of Bacillus inoculation in rice straw composting and bacterial community stability after inoculation: Unite resistance or individual collapse
S Zhang, T Xia, J Wang, Y Zhao, X Xie, Z Wei… - Bioresource …, 2021 - Elsevier
Bacillus is the classic inoculant in rice straw composting. However, there has been no in-
depth study of the mechanism promoting the degradation of lignocellulose and the change …
depth study of the mechanism promoting the degradation of lignocellulose and the change …
M6AREG: m6A-centered regulation of disease development and drug response
As the most prevalent internal modification in eukaryotic RNAs, N 6-methyladenosine (m6A)
has been discovered to play an essential role in cellular proliferation, metabolic …
has been discovered to play an essential role in cellular proliferation, metabolic …