Bioactivity assessment and toxicity of crocin: a comprehensive review

SH Alavizadeh, H Hosseinzadeh - Food and chemical toxicology, 2014 - Elsevier
Since ancient times, saffron, the dried stigma of the plant Crocus sativus L. has been
extensively used as a spice and food colorant; in folk medicine it has been reputed to be …

Chemical and biological properties of the world's most expensive spice: Saffron

JP Melnyk, S Wang, MF Marcone - Food research international, 2010 - Elsevier
Saffron (Crocus sativus, L.) is traditionally used as a coloring or flavoring agent, but recent
research has shown its potential to promote health. The constituents of interest include …

Retention of saffron bioactive components by spray drying encapsulation using maltodextrin, gum Arabic and gelatin as wall materials

H Rajabi, M Ghorbani, SM Jafari, AS Mahoonak… - Food hydrocolloids, 2015 - Elsevier
Saffron as the world's most expensive spice is very sensitive and loses its active compounds
in exposure to environmental conditions. In this work, microencapsulation of saffron extract …

Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.)

FI Abdullaev - Experimental biology and medicine, 2002 - journals.sagepub.com
Since cancer is the most common cause of death in the world population, the possibility that
readily available natural substances from plants, vegetables, herbs, and spices may be …

New applications and mechanisms of action of saffron and its important ingredients

SZ Bathaie, SZ Mousavi - Critical reviews in food science and …, 2010 - Taylor & Francis
Saffron (Crocus sativus L.) has been an important subject of interest for research teams in
the past two decades because of its various biological properties. Chemical analysis has …

Saffron—renewed interest in an ancient spice

P Winterhalter, M Straubinger - Food Reviews International, 2000 - Taylor & Francis
Research into the chemical composition of saffron, the dried stigmas of Crocus sativus, has
seen a renaissance in recent years. Different HPLC protocols for the analysis of saffron …

Molecular mechanisms behind safranal's toxicity to HepG2 cells from dual omics

DR Nelson, AA Hrout, AS Alzahmi, A Chaiboonchoe… - Antioxidants, 2022 - mdpi.com
The spice saffron (Crocus sativus) has anticancer activity in several human tissues, but the
molecular mechanisms underlying its potential therapeutic effects are poorly understood …

Determination of saffron (Crocus sativus L.) components in crude plant extract using high-performance liquid chromatography-UV-visible photodiode-array detection …

PA Tarantilis, G Tsoupras, M Polissiou - Journal of Chromatography A, 1995 - Elsevier
The determination of saffron components in crude plant extracts by high-performance liquid
chromatography-UV-visible photodiode-array detection on-line with mass spectrometry is …

Main chemical compounds and pharmacological activities of stigmas and tepals of 'red gold'; saffron

T Shahi, E Assadpour, SM Jafari - Trends in Food Science & Technology, 2016 - Elsevier
Background Crocus sativus L.(saffron) belongs to Iridaceae family which is commonly
cultivated in Asia, Europe and America. The commercial product and use of saffron comes …

Biologically active compounds and pharmacological activities of species of the genus Crocus: A review

O Mykhailenko, V Kovalyov, O Goryacha, L Ivanauskas… - Phytochemistry, 2019 - Elsevier
The present article is the first comprehensive review on the chemical composition and
pharmacological activities of the raw materials of Crocus species. In the present review, data …