Through coevolution with host cells, microorganisms have acquired mechanisms to avoid
the detection by the host surveillance system and to use the cell's supplies to establish …

It is becoming increasingly clear that eukaryotic cell physiology is largely controlled by
protein–protein interactions involving disordered protein regions, which usually interact with …

Studies on the DNA-binding properties of transcription factors are important in searching for
the downstream genes regulated by these factors. In the present study, we report on the …

Abstract The Eukaryotic Linear Motif (ELM) resource (http://elm. eu. org) is a manually
curated database of short linear motifs (SLiMs). In this update, we present the latest …

Short linear motifs (SLiMs) are protein binding modules that play major roles in almost all
cellular processes. SLiMs are short, often highly degenerate, difficult to characterize and …

Viral proteins make extensive use of short peptide interaction motifs to hijack cellular host
factors. However, most current large-scale methods do not identify this important class of …

Since the inception of the human microbiome project (HMP) by the US National Institutes of
Health (NIH) in 2007 there has been a keen resurgence in our recognition of the human …

The intrinsically disordered regions of eukaryotic proteomes are enriched in short linear
motifs (SL iMs), which are of crucial relevance for cellular signaling and protein regulation; …

The virus interacts with its hosts by developing protein-protein interactions. Most viruses
employ protein interactions to imitate the host protein: A viral protein with the same amino …

The genome of Mycobacterium tuberculosis, the causal organism of tuberculosis (TB),
encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in …