Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the
presence of one or more cold shock domains. In humans, the best characterized members of …

Simple Summary Proteins are composed of compact domains, often of known three-
dimensional structure, and natively unstructured polypeptide regions. The abundant cold …

The assembly of cortical circuits involves the generation and migration of interneurons from
the ventral to the dorsal forebrain,–, which has been challenging to study at inaccessible …

Glial cells have been proposed as a source of neural progenitors, but the mechanisms
underpinning the neurogenic potential of adult glia are not known. Using single cell …

Induced pluripotent stem cells (iPSCs) undergo unlimited self-renewal while maintaining
their potential to differentiate into post-mitotic cells with an intact proteome. As such, iPSCs …

CAG-repeat expansions in at least eight different genes cause neurodegeneration. The
length of the extended polyglutamine stretches in the corresponding proteins is …

Aging is a primary risk factor for neurodegenerative disorders that involve protein
aggregation. Because lowering body temperature is one of the most effective mechanisms to …

APOBEC3B, an anti-viral cytidine deaminase which induces DNA mutations, has been
implicated as a mediator of cancer evolution and therapeutic resistance. Mutational plasticity …

The cell-context dependency for RNA binding proteins (RBPs) mediated control of stem cell
fate remains to be defined. Here we adapt the HyperTRIBE method using an RBP fused to a …

Fatty acid binding proteins (FABPs) are key regulators of lipid metabolism, energy
homeostasis, and inflammation. They participate in fatty acid metabolism by regulating their …