The Beneficial Role of Apigenin against Cognitive and Neurobehavioural Dysfunction: A Systematic Review of Preclinical Investigations

TA Olasehinde, OO Olaokun - Biomedicines, 2024 - mdpi.com
Apigenin is a flavone widely present in different fruits and vegetables and has been
suggested to possess neuroprotective effects against some neurological disorders. In this …

Apigenin: A Bioflavonoid with a Promising Role in Disease Prevention and Treatment

KS Allemailem, A Almatroudi, HOA Alharbi… - Biomedicines, 2024 - mdpi.com
Apigenin is a powerful flavone compound found in numerous fruits and vegetables, and it
offers numerous health-promoting benefits. Many studies have evidenced that this …

Synthesis, Molecular Electron Density Theory Study, Molecular Docking, and Pharmacological Evaluation of New Coumarin–Sulfonamide–Nitroindazolyl–Triazole …

M Eddahmi, G La Spada, LR Domingo… - International Journal of …, 2024 - mdpi.com
Inhibitors of monoamine oxidases (MAOs) are of interest for the treatment of
neurodegenerative disorders and other human pathologies. In this frame, the present work …

PCSK9 inhibitors as safer therapeutics for atherosclerotic cardiovascular disease (ASCVD): Pharmacophore design and molecular dynamics analysis

IO Kehinde, O Akawa, AT Adewumi… - Journal of Cellular …, 2024 - Wiley Online Library
Cardiovascular disorders are still challenging and are among the deadly diseases. As a
major risk factor for atherosclerotic cardiovascular disease, dyslipidemia, and high low …

Apigenin exhibits memory enhancing activity through the restoration of oxido-endocrine balance and upregulation of BDNF/ERK/CREB signalling pathways in …

JN Olayinka, AT Eduviere, MO Okosun… - Naunyn-Schmiedeberg's …, 2025 - Springer
Stress is linked to oxidative imbalance, neuroendocrine system malfunction, and cognitive
dysfunction. It is a recognized cause of neuropsychiatric diseases. Natural flavonoid …

Molecular Docking Analysis Reveals the Promising Role of Apigenin as a Potential Treatment for Neurological Disorders

M Wasim, SR Zia, S Ahmad - Clinical Neuropharmacology, 2024 - journals.lww.com
Objectives Neurological disorders represent a significant global health challenge,
necessitating the exploration of novel therapeutic agents. Apigenin, a natural flavonoid …

A dive into natural leads against depression from family Lamiaceae

P Singh, U Kaushik - Journal of Applied Pharmaceutical Science, 2024 - japsonline.com
One of the most significant herbal families, the Lamiaceae, has a vast range of plants having
biological and therapeutic uses. Due to its curative and preventative qualities, species of the …

Unveiling Nature's Arsenal: Natural Sources for Drug Discovery in Alzheimer's Disease

C Remya, N Aiswarya, KV Dileep - Drugs from Nature: Targets, Assay …, 2024 - Springer
Alzheimer's disease (AD) imposes a significant global healthcare challenge, as it currently
lacks a definitive cure. This devastating condition disrupts cognitive function, eroding …

[PDF][PDF] Does Combining Mycoplasma and SARS-CoV-2 Virus Comprise a Binary Biological Weapon? A Psychiatrist's Perspective

A Sfera, JJ Anton, S Hazan - 2024 - preprints.org
Mycoplasma is the smallest, independently replicating microbe that lacks a cell wall and
resembles a liposome because of its sterol-rich cell membrane. Under pathological …