Mesenchymal stem cell-released oncolytic virus: an innovative strategy for cancer treatment

N Ghasemi Darestani, AI Gilmanova… - Cell Communication and …, 2023 - Springer
Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no
damage to normal cells in the process. Because of their specific features, such as, the ability …

[HTML][HTML] Stem cells in cancer therapy: opportunities and challenges

CL Zhang, T Huang, BL Wu, WX He, D Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Metastatic cancer cells generally cannot be eradicated using traditional surgical or
chemoradiotherapeutic strategies, and disease recurrence is extremely common following …

[HTML][HTML] Recent advances in regenerative medicine strategies for cancer treatment

V Mansouri, N Beheshtizadeh, M Gharibshahian… - Biomedicine & …, 2021 - Elsevier
Cancer stands as one of the most leading causes of death worldwide, while one of the most
significant challenges in treating it is revealing novel alternatives to predict, diagnose, and …

The influence of the blood–brain barrier in the treatment of brain tumours

S Rathi, JI Griffith, W Zhang, W Zhang… - Journal of Internal …, 2022 - Wiley Online Library
Brain tumours have a poor prognosis and lack effective treatments. The blood–brain barrier
(BBB) represents a major hurdle to drug delivery to brain tumours. In some locations in the …

Drug delivery with living cells

LAL Fliervoet, E Mastrobattista - Advanced drug delivery reviews, 2016 - Elsevier
The field of drug delivery has grown tremendously in the past few decades by developing a
wide range of advanced drug delivery systems. An interesting category is cell-based drug …

Pathophysiology of blood-brain barrier in brain tumor. Novel therapeutic advances using nanomedicine

HS Sharma, DF Muresanu, A Nozari… - International review of …, 2020 - Elsevier
Glioblastoma Multiforme (GBM) is one the most common intracranial tumors discovered by
Burns (1800) and Abernethy (1804) based on gross morphology of the autopsied material …

Cytopharmaceuticals: an emerging paradigm for drug delivery

W Li, Z Su, M Hao, C Ju, C Zhang - Journal of Controlled Release, 2020 - Elsevier
Cytopharmaceuticals, in which drugs/nanomedicines are loaded into/onto autologous
patient-or allogeneic donor-derived living cells ex vivo, have displayed great promise for …

Development of a biocompatible 3D hydrogel scaffold using continuous liquid interface production for the delivery of cell therapies to treat recurrent glioblastoma

L Kass, M Thang, Y Zhang, C DeVane… - Bioengineering & …, 2024 - Wiley Online Library
Glioblastoma (GBM) is the most common primary malignant brain tumor diagnosed in adults,
carrying with it an extremely poor prognosis and limited options for effective treatment …

Porous and responsive hydrogels for cell therapy

L Wang, M Neumann, T Fu, W Li, X Cheng… - Current Opinion in Colloid …, 2018 - Elsevier
Cell therapy is an emerging and promising regenerative approach by cell replacement for
the treatment of diseases or injuries. Hydrogels, featuring high biocompatibility, tunable …

Delivery strategies for cell-based therapies in the brain: overcoming multiple barriers

OM Turk, RC Woodall, M Gutova, CE Brown… - Drug delivery and …, 2021 - Springer
Cell-based therapies to the brain are promising for the treatment of multiple brain disorders
including neurodegeneration and cancers. In order to access the brain parenchyma, there …