Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …

We can claim that we know what the visual system does once we can predict neural
responses to arbitrary stimuli, including those seen in nature. In the early visual system …

Brain organoids created from human pluripotent stem cells represent a promising approach
for brain repair. They acquire many structural features of the brain and raise the possibility of …

This review attempts to summarise some of the major areas of neocortical research as it
pertains to layer 6. After a brief summary of the development of this intriguing layer, the …

Ever since Hubel and Wiesel described orientation selectivity in the visual cortex, the
question of how precise selectivity emerges has been marked by considerable debate …

Visual cortex shows smooth retinotopic organization on the macroscopic scale, but it is
unknown how receptive fields are organized at the level of neighboring neurons. This …

Multisensory integration (MI) is crucial for sensory processing, but it is unclear how MI is
organized in cortical microcircuits. Whole-cell recordings in a mouse visuotactile area …

Understanding how cortical activity generates sensory perceptions requires a detailed
dissection of the function of cortical layers. Despite our relatively extensive knowledge of …

The primary visual cortex contains a detailed map of the visual scene, which is represented
according to multiple stimulus dimensions including spatial location, ocular dominance and …

Simple cells in primary visual cortex exhibit contrast-invariant orientation tuning, in seeming
contradiction to feed-forward models that rely on lateral geniculate nucleus (LGN) input …