Animal models of adult-onset neurodegenerative diseases have enhanced the
understanding of the molecular pathogenesis of Alzheimer's disease, Parkinson's disease …

Mitochondrial dysfunction represents a well-established player in the pathogenesis of both
monogenic and idiopathic Parkinson's disease (PD). Initially originating from the observation …

The dynamic and multicellular processes of neuroinflammation are mediated by the
nonneuronal cells of the central nervous system, which include astrocytes and the brain's …

The use of animals as models of human physiology is, and has been for many years, an
indispensable tool for understanding the mechanisms of human disease. In Parkinson's …

Parkinson's disease (PD) is the second most common neurodegenerative disorder.
However, therapeutic options treating only its symptoms are very disappointing. Therefore …

Despite decades of research, accurate diagnosis of Parkinson's disease remains a
challenge, and disease-modifying treatments are still lacking. Research into the early …

A wide variety of human diseases have been modelled in zebrafish, including various types
of cancer, cardiovascular diseases and neurodegenerative diseases like Alzheimer's and …

Purpose of the study The aim of this study is to evaluate the effect of apigenin on
inflammatory response in brain tissue in Parkinson's mouse model. Materials and methods …

Abstract In Persian Medicine (PM), PD (brain‐based tremor) is a known CNS disorder with
several therapeutic and preventive options. In their medical textbooks and pharmacopeias …

Parkinson's disease (PD) is a widespread neurodegenerative condition affecting millions
globally. This investigation centered on the gut-brain axis in a rotenone-induced PD rat …