Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy

G Sloan, D Selvarajah, S Tesfaye - Nature Reviews Endocrinology, 2021 - nature.com
Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

[HTML][HTML] Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links

OO Oguntibeju - International journal of physiology …, 2019 - ncbi.nlm.nih.gov
Diabetes mellitus has been recognised as one of the four major non-communicable
diseases that demands urgent attention from all key shareholders globally in an effort to …

Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies

R Kaur, M Kaur, J Singh - Cardiovascular diabetology, 2018 - Springer
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

[HTML][HTML] Diabetes mellitus: The epidemic of the century

AT Kharroubi, HM Darwish - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
The epidemic nature of diabetes mellitus in different regions is reviewed. The Middle East
and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas …

Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets

S Dewanjee, S Das, AK Das, N Bhattacharjee… - European journal of …, 2018 - Elsevier
Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Peripheral neuropathy in diabetes mellitus: pathogenetic mechanisms and diagnostic options

R Galiero, A Caturano, E Vetrano, D Beccia… - International Journal of …, 2023 - mdpi.com
Diabetic neuropathy (DN) is one of the main microvascular complications of both type 1 and
type 2 diabetes mellitus. Sometimes, this could already be present at the time of diagnosis …

Diabetic neuropathy: clinical manifestations and current treatments

BC Callaghan, HT Cheng, CL Stables… - The lancet …, 2012 - thelancet.com
Diabetic peripheral neuropathy is a prevalent, disabling disorder. The most common
manifestation is distal symmetrical polyneuropathy (DSP), but many patterns of nerve injury …

Topical Citrullus colocynthis (bitter apple) extract oil in painful diabetic neuropathy: A double‐blind randomized placebo‐controlled clinical trial 外用西瓜属药西瓜瓤 …

M Heydari, K Homayouni, MH Hashempur… - Journal of …, 2016 - Wiley Online Library
摘要背景当前这项研究的目的是在痛性糖尿病神经病变(painful diabetic polyneuropathy,
PDPN) 患者中调查一种西瓜属药西瓜瓤(Citrullus colocynthis) 外用制剂的安全性与有效性 …

Diabetic neuropathy: mechanisms, emerging treatments, and subtypes

JW Albers, R Pop-Busui - Current neurology and neuroscience reports, 2014 - Springer
Diabetic neuropathies (DNs) differ in clinical course, distribution, fiber involvement (type and
size), and pathophysiology, the most typical type being a length-dependent distal symmetric …

Factors affecting wound healing

S Guo, LA DiPietro - Journal of dental research, 2010 - journals.sagepub.com
Wound healing, as a normal biological process in the human body, is achieved through four
precisely and highly programmed phases: hemostasis, inflammation, proliferation, and …