Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-
derived nucleic acids and respond with rapid and massive production of type I interferon …

Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …

Plasmacytoid dendritic cells (pDCs) represent a unique cell type within the innate immune
system. Their defining property is the recognition of pathogen-derived nucleic acids through …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive and largely
incurable hematologic malignancy originating from plasmacytoid dendritic cells (pDCs) …

One of the most powerful and multifaceted cytokines produced by immune cells are type I
interferons (IFNs), the basal secretion of which contributes to the maintenance of immune …

In addition to neuroprotective strategies, neuroregenerative processes could provide targets
for stroke recovery. However, the upregulation of inhibitory chondroitin sulfate proteoglycans …

Purpose: MYD88 mutations, notably the recurrent gain-of-function L265P variant, are a
distinguishing feature of activated B-cell like (ABC) diffuse large B-cell lymphoma (DLBCL) …

The liver is a multitasking organ with essential functions for vertebrate health spanning
metabolism and immunity. In contrast to mammals, our understanding of liver cellular …

Gallbladder carcinoma (GBC) is the most common biliary tract malignancy with the lowest
survival rate, primarily arising from chronic inflammation. To better characterize the …

The endometrium undergoes regular regeneration and stromal proliferation as part of the
normal menstrual cycle. To better understand cellular interactions driving the mechanisms in …