Type VI secretion system effectors: poisons with a purpose

AB Russell, SB Peterson, JD Mougous - Nature reviews microbiology, 2014 - nature.com
The type VI secretion system (T6SS) mediates interactions between a broad range of Gram-
negative bacterial species. Recent studies have led to a substantial increase in the number …

Melioidosis: a clinical overview

D Limmathurotsakul, SJ Peacock - British medical bulletin, 2011 - academic.oup.com
Introduction melioidosis, an infection caused by the environmental Gram-negative bacillus
Burkholderia pseudomallei, has emerged as an important cause of morbidity and mortality in …

Human melioidosis

I Gassiep, M Armstrong, R Norton - Clinical microbiology reviews, 2020 - Am Soc Microbiol
The causative agent of melioidosis, Burkholderia pseudomallei, a tier 1 select agent, is
endemic in Southeast Asia and northern Australia, with increased incidence associated with …

Systematic Review and Consensus Guidelines for Environmental Sampling of Burkholderia pseudomallei

D Limmathurotsakul, DAB Dance… - PLoS neglected …, 2013 - journals.plos.org
Background Burkholderia pseudomallei, a Tier 1 Select Agent and the cause of melioidosis,
is a Gram-negative bacillus present in the environment in many tropical countries. Defining …

Trimethoprim-sulfamethoxazole versus trimethoprim-sulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): a multicentre, double …

P Chetchotisakd, W Chierakul, W Chaowagul… - The Lancet, 2014 - thelancet.com
Background Melioidosis, an infectious disease caused by the Gram-negative bacillus
Burkholderia pseudomallei, is difficult to cure. Antimicrobial treatment comprises intravenous …

Melioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes

SJ Peacock, D Limmathurotsakul, Y Lubell… - PLoS neglected …, 2012 - journals.plos.org
Background Burkholderia pseudomallei is a Category B select agent and the cause of
melioidosis. Research funding for vaccine development has largely considered protection …

The toxin/immunity network of Burkholderia pseudomallei contact‐dependent growth inhibition (CDI) systems

K Nikolakakis, S Amber, JS Wilbur… - Molecular …, 2012 - Wiley Online Library
Burkholderia pseudomallei is a category B pathogen and the causative agent of melioidosis–
a serious infectious disease that is typically acquired directly from environmental reservoirs …

The dynamic genetic repertoire of microbial communities

P Wilmes, SL Simmons, VJ Denef… - FEMS microbiology …, 2008 - academic.oup.com
Community genomic data have revealed multiple levels of variation between and within
microbial consortia. This variation includes large-scale differences in gene content between …

Comparison of O-polysaccharide and hemolysin co-regulated protein as target antigens for serodiagnosis of melioidosis

A Pumpuang, SJ Dunachie, P Phokrai… - PLoS neglected …, 2017 - journals.plos.org
Background Melioidosis is a severe disease caused by Burkholderia pseudomallei. Clinical
manifestations are diverse and acute infections require immediate treatment with effective …

[HTML][HTML] Antibodies in melioidosis: the role of the indirect hemagglutination assay in evaluating patients and exposed populations

P Chaichana, K Jenjaroen, P Amornchai… - The American journal …, 2018 - ncbi.nlm.nih.gov
Melioidosis is a major neglected tropical disease with high mortality, caused by the Gram-
negative bacterium Burkholderia pseudomallei (Bp). Microbiological culture remains the …