The aim of this paper is to review and evaluate, in a comprehensive manner, the published
data regarding the contribution of genetic polymorphisms to risk of esophageal cancer …

In gastric cancer (GC) the loss of genomic stability represents a key molecular step that
occurs early in the carcinogenesis process and creates a permissive environment for the …

Background Unlike other human tumors, gastric cancer remains a great therapeutic
challenge since no standardized postoperative treatment exists. Knowledge of molecular …

Microsatellite instability (MSI)–high gastric cancers (GC) have better prognosis and higher
levels of tumor-infiltrating lymphocytes (TIL) compared with MSI-low or MSI-stable GCs. TILs …

Background In gastric cancer, the recurrence rate is high even after curative surgery. A
relevant issue is the identification of independent prognostic factors to select high‐risk …

Gastric cancer is one of the leading causes of cancer-related deaths worldwide, although
the incidence has gradually decreased in many Western countries. Two main gastric cancer …

Currently, gastric cancer (GC) is one of the most frequently diagnosed neoplasms, with a
global burden of 723000 deaths in 2012. It is the third leading cause of cancer-related death …

The phenomenon of cancer metastasis remains poorly understood. We discuss here various
conceptual frameworks that attempt to rationalize the mechanisms by which tumors acquire …

Microsatellite instability (MSI) is a major pathway involved in gastric carcinogenesis
occurring in 20% of gastric cancer (GC). However, it is not clear whether MSI phenotype …

The aim of this report is to review and evaluate, in a comprehensive manner, the published
data regarding the contribution of genetic polymorphisms to risk of head and neck cancer …