[HTML][HTML] Mitochondria targeting drugs for neurodegenerative diseases—Design, mechanism and application

J Xu, W Du, Y Zhao, K Lim, L Lu, C Zhang… - Acta Pharmaceutica Sinica …, 2022 - Elsevier
Neurodegenerative diseases (NDDs) such as Alzheimer's disease (AD) and Parkinson's
disease (PD) are a heterogeneous group of disorders characterized by progressive …

Stem cell therapy for retinal degeneration: the evidence to date

A Sharma, BG Jaganathan - Biologics: Targets and Therapy, 2021 - Taylor & Francis
There is a rise in the number of people who have vision loss due to retinal diseases, and
conventional therapies for treating retinal degeneration fail to repair and regenerate the …

A review on mesenchymal stem cells for treatment of retinal diseases

S Adak, D Magdalene, S Deshmukh, D Das… - Stem cell reviews and …, 2021 - Springer
Abstract Mesenchymal Stem Cells (MSCs) have been studied extensively for the treatment
of several retinal diseases. The therapeutic potential of MSCs lies in its ability to differentiate …

[HTML][HTML] Potential therapeutic applications of mesenchymal stem cells for the treatment of eye diseases

G Mannino, C Russo, A Longo, CD Anfuso… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
Stem cell-based treatments have been extensively explored in the last few decades to
develop therapeutic strategies aimed at providing effective alternatives for those human …

[HTML][HTML] Pigment epithelium-derived factor and its role in microvascular-related diseases

Y Wang, X Liu, X Quan, X Qin, Y Zhou, Z Liu, Z Chao… - Biochimie, 2022 - Elsevier
Microvascular diseases are among the most clinically important diseases, and vascular
abnormalities are central in the development of such diseases. Pigment epithelium-derived …

Mesenchymal stem cells as a gene delivery tool: Promise, problems, and prospects

N Attia, M Mashal, G Puras, JL Pedraz - Pharmaceutics, 2021 - mdpi.com
The cell-based approach in gene therapy arises as a promising strategy to provide safe,
targeted, and efficient gene delivery. Owing to their unique features, as homing and tumor …

PGC‐1α protects from myocardial ischaemia‐reperfusion injury by regulating mitonuclear communication

YQ Li, Y Jiao, YN Liu, J Fu, LK Sun… - Journal of Cellular and …, 2022 - Wiley Online Library
The recovery of blood supply after a period of myocardial ischaemia does not restore the
heart function and instead results in a serious dysfunction called myocardial ischaemia …

[HTML][HTML] Achyranthis radix Extract Enhances Antioxidant Effect of Placenta-Derived Mesenchymal Stem Cell on Injured Human Ocular Cells

DH Lee, JW Han, H Park, SJ Hong, CS Kim, YS Kim… - Cells, 2024 - mdpi.com
Age-related ocular diseases such as age-related macular degeneration, glaucoma, and
diabetic retinopathy are major causes of irreversible vision impairment in the elderly …

Metabolic mechanisms and potential therapeutic targets for prevention of ovarian aging: data from up-to-date experimental studies

K Valtetsiotis, G Valsamakis, E Charmandari… - International Journal of …, 2023 - mdpi.com
Female infertility and reproduction is an ongoing and rising healthcare issue, resulting in
delaying the decision to start a family. Therefore, in this review, we examine potential novel …

[HTML][HTML] Mitochondria in Retinal Ganglion Cells: Unraveling the Metabolic Nexus and Oxidative Stress

TH Yang, EYC Kang, PH Lin, BBC Yu… - International Journal of …, 2024 - mdpi.com
This review explored the role of mitochondria in retinal ganglion cells (RGCs), which are
essential for visual processing. Mitochondrial dysfunction is a key factor in the pathogenesis …