M Pariyar, A Johns, RF Thorne, RJ Scott… - Neoplasia, 2021 - Elsevier
Triple negative breast cancer (TNBC) is a highly metastatic and aggressive subtype of breast cancer and cases presenting with lymph node involvement have worse outcomes …
A Gonzalez-Reymundez, AI Vázquez - Scientific reports, 2020 - nature.com
Despite recent advances in treatment, cancer continues to be one of the most lethal human maladies. One of the challenges of cancer treatment is the diversity among similar tumors …
C Ross, K Szczepanek, M Lee, H Yang, T Qiu… - PLoS …, 2020 - journals.plos.org
Metastasis remains the principle cause of mortality for breast cancer and presents a critical challenge because secondary lesions are often refractory to conventional treatments. While …
M Ebrahimpoor, R Menezes, N Xu… - arXiv preprint arXiv …, 2024 - arxiv.org
Integrated analysis of multi-omics datasets holds great promise for uncovering complex biological processes. However, the large dimension of omics data poses significant …
The need of identifying alternative therapeutic targets for invasive ductal carcinoma (IDC) of the breast with high specificity and sensitivity for effective therapeutic intervention is crucial …
S Mukerjee, A Gonzalez-Reymundez, SY Lunt… - Cancer …, 2020 - Taylor & Francis
Pancreatic cancer (PC) is associated with a high mortality rate. We explored the interindividual variation of cancer outcomes, attributable to DNA methylation, gene …
Knowing metastasis is the primary cause of cancer-related deaths incentivized research to unravel the complex cellular processes that drive the metastasis. Advancement in …
The increasing volume of high-dimensional biological data (omics) has intensified the discovery of thousands of biomarkers across the different fundamental components of the …
Introduction: Selection and evolution of tumour cells occurs during cancer progression and metastasis. Understanding the mechanism of clonal dynamics and evolution is an important …