BDNF as a biomarker for successful treatment of mood disorders: a systematic & quantitative meta-analysis

M Polyakova, K Stuke, K Schuemberg, K Mueller… - Journal of affective …, 2015 - Elsevier
Background Peripheral brain-derived neurotrophic factor (BDNF) is decreased in acute
major depressive disorder (MDD) and bipolar disorder (BD) and recovered after treatment …

Neuroplasticity—exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects

K Knaepen, M Goekint, EM Heyman, R Meeusen - Sports medicine, 2010 - Springer
Exercise is known to induce a cascade of molecular and cellular processes that support
brain plasticity. Brain-derived neurotrophic factor (BDNF) is an essential neurotrophin that is …

Psychedelics and neural plasticity: therapeutic implications

SF Grieco, E Castrén, GM Knudsen… - Journal of …, 2022 - Soc Neuroscience
Psychedelic drugs have reemerged as tools to treat several brain disorders. Cultural
attitudes toward them are changing, and scientists are once again investigating the neural …

Dose–response matters!–a perspective on the exercise prescription in exercise–cognition research

F Herold, P Müller, T Gronwald, NG Müller - Frontiers in psychology, 2019 - frontiersin.org
In general, it is well recognized that both acute physical exercises and regular physical
training influence brain plasticity and cognitive functions positively. However, growing …

Blood BDNF concentrations reflect brain-tissue BDNF levels across species

AB Klein, R Williamson, MA Santini… - International Journal …, 2011 - academic.oup.com
Brain-derived neurotrophic factor (BDNF) is involved in synaptic plasticity, neuronal
differentiation and survival of neurons. Observations of decreased serum BDNF levels in …

Associations between serum and plasma brain-derived neurotrophic factor and influence of storage time and centrifugation strategy

AK Gejl, C Enevold, A Bugge, MS Andersen… - Scientific reports, 2019 - nature.com
The aims of the study were to clarify the impact of storage time and centrifugation strategy on
brain-derived neurotrophic factor (BDNF) levels in human serum and plasma samples. In …

A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression

AR Brunoni, M Lopes, F Fregni - International Journal of …, 2008 - academic.oup.com
Several clinical studies on major depressive disorder (MDD) have shown that blood brain-
derived neurotrophic factor (BDNF)–a factor used to index neuroplasticity–is associated with …

A method for reproducible measurements of serum BDNF: comparison of the performance of six commercial assays

A Polacchini, G Metelli, R Francavilla, G Baj… - Scientific reports, 2015 - nature.com
Abstract Brain-Derived Neurotrophic Factor (BDNF) has attracted increasing interest as
potential biomarker to support the diagnosis or monitor the efficacy of therapies in brain …

BDNF responses in healthy older persons to 35 minutes of physical exercise, cognitive training, and mindfulness: associations with working memory function

K Håkansson, A Ledreux, K Daffner… - Journal of …, 2016 - journals.sagepub.com
Brain-derived neurotrophic factor (BDNF) has a central role in brain plasticity by mediating
changes in cortical thickness and synaptic density in response to physical activity and …

Serum levels of brain-derived neurotrophic factor in major depressive disorder: state–trait issues, clinical features and pharmacological treatment

ML Molendijk, BA Bus, P Spinhoven… - Molecular …, 2011 - nature.com
Recent evidence supports 'the neurotrophin hypothesis of depression'in its prediction that
brain-derived neurotrophic factor (BDNF) is involved in depression. However, some key …