The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …

Prostate cancer surgery is currently being revolutionized by the use of prostate-specific
membrane antigen (PSMA)–targeted radiotracers, for example, 99mTc-labeled PSMA tracer …

Cancer imaging is a rapidly evolving field due to the discovery of novel molecular targets
and the availability of corresponding techniques to detect them with high precision …

Type 2 immunity plays an essential role in the maintenance of metabolic homeostasis and
its disruption during obesity promotes meta‐inflammation and insulin resistance. Infection …

Strain-promoted azide–alkyne cycloaddition (SPAAC) is a straightforward and multipurpose
conjugation strategy. The use of SPAAC to link different functional elements to prostate …

Aim: Pre-targeting is a proven strategy for in vivo delivery of a diagnostic or therapeutic
payload. The pre-targeting concept can be realized through various conjugation strategies …

Herein, we present a straightforward synthetic route for the design and synthesis of diverse
heterobifunctional cyanine 5 dyes. We optimized the workup by harnessing the pH-and …

Pentamethine cyanine (Cy5) fluorophores have proven to be versatile imaging agents (ie,
tracers) for a range of micro-and macroscopic imaging applications, including image-guided …

Monolayer-protected gold nanoclusters (AuNCs) are atomically precise assemblies less
than 2 nanometers in diameter, giving them size-specific physical and chemical properties …

Real-time intraoperatieve begeleiding tijdens prostaatkankerchirurgie kan helpen bij de
realisatie van een volledige en veilige resectie van de primaire tumor en/of de …