Almost 15 years ago it was hypothesized that polymorphisms of genes encoding enzymes
involved in folate metabolism could lead to aberrant methylation of peri-centromeric regions …

Abstract Background In July 2004, the Brazilian Ministry of Health through the National
Health Surveillance Agency made the fortification of wheat flour and cornmeal (maize flour) …

Recent researches have investigated the factors that determine the maternal risk for Down
syndrome (DS) in young woman. In this context, some studies have demonstrated the …

Down syndrome (DS) is the most common chromosomal disorder, resulting from the failure
of normal chromosome 21 segregation. Studies have suggested that impairments within the …

Background: Down syndrome (DS) results from the presence and expression of three copies
of the genes located on chromosome 21. Studies have shown that, in addition to …

Down syndrome (DS) or trisomy 21 (MIM 190685) is the most common genetic disorder with
a prevalence of 1 in 660 live births (Jones, 2006). DS is the leading cause of …

Trisomy 21, the common chromosomal abnormality leading to Down syndrome, has become
an important model for human chromosome nondisjunction. Here we review studies of the …

Down syndrome (DS) is the most common form of mental disability of genetic etiology.
Nondisjunction of chromosome 21 is the leading cause of the syndrome. In general, free …

DNA methylation is an important epigenetic determinant in gene expression, aberrancies of
which are mechanistically related to the development of several diseases. During …

O objetivo deste estudo foi analisar e comparar o perfil antropométrico e postural de
adolescentes com Síndrome de Down (SD). A amostra foi composta por 36 indivíduos …