Reactive Oxygen Species or “ROS” encompass several molecules derived from oxygen that
can oxidize other molecules and subsequently transition rapidly between species. The key …

Cancer research of the Warburg effect, a hallmark metabolic alteration in tumors, focused
attention on glucose metabolism whose targeting uncovered several agents with promising …

In the 1920s, Otto Warburg observed the phenomenon of altered glucose metabolism in
cancer cells. Although the initial hypothesis suggested that the alteration resulted from …

Glucose, the primary substrate for ATP synthesis, is catabolized during glycolysis to
generate ATP and precursors for the synthesis of other vital biomolecules. Opportunistic …

Angiogenesis is a complex process describing the growth of new blood vessels from
existing vasculature, and is triggered by local pro-angiogenic factors, such as vascular …

Psoriasis is a common chronic disease with accelerated epidermal cell growth. Solute
carrier family 2 member 1 (SLC 2A1), also named GLUT 1, transports glucose and its …

Pancreatic cancer (PC) has a poor prognosis owing to difficulties in the diagnosis of
resectable PC at early stages. Several clinical studies have indicated that the detection and …

Hepatocellular carcinoma (HCC) significantly contributes to cancer‐related mortality due to
the limited response of HCC to current anticancer therapies, thereby necessitating more …

Abstract Information about poorly reactive metabolites, lactate and glucose could be
encoded into DNA sequences. The sequential reaction steps, including H2O2 generation …

Fluorodeoxyglucose (FDG) is a glucose derivative with fluorine at the C 2 position. The
molecule containing the radioactive F-18 isotope is well known from its application in …