The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …

Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

The problem of antibiotic resistance among pathogenic bacteria has reached a crisis level.
The treatment options against infections caused by multiple drug-resistant bacteria are …

The molecular hybridization approach has been used to develop compounds with improved
efficacy by combining two or more pharmacophores of bioactive scaffolds. In this context …

Antibiotic resistance (AR) is a silent pandemic that kills millions worldwide. Although the
development of new therapeutic agents against antibiotic resistance is in urgent demand …

Klebsiella pneumoniae is a multidrug-resistant (MDR) opportunistic pathogen that causes
nosocomial infections. Virulence analysis and molecular typing as powerful approaches can …

Bacterial infection is a common clinical disease. Antibiotics have saved countless lives since
their discovery and are a powerful weapon in the fight against bacteria. However, with the …

Antiviral drugs are used globally as treatment and prophylaxis for long-term and acute viral
infections. Even though antivirals also have been shown to have off-target effects on …

Introduction: SARS-CoV2 pandemic marks the need to pay attention to bacterial pathogens
that can complicate the hospital stay of patients in the intensive care unit (ICU). ESKAPE …