[HTML][HTML] Overview the effect of statin therapy on dementia risk, cognitive changes and its pathologic change: a systematic review and meta-analysis

XC Zhu, WZ Dai, T Ma - Annals of Translational Medicine, 2018 - ncbi.nlm.nih.gov
Background Many studies have reported on the role of statin therapy in dementia, but its
efficacy remains controversial. We aimed to search for reliable and meaningful articles to …

D-galactose-induced aging in rats–The effect of metformin on bioenergetics of brain, skeletal muscle and liver

Z Sumbalová, O Uličná, J Kucharská, Z Rausová… - Experimental …, 2022 - Elsevier
Chronic D-galactose administration induces accelerated aging in rodents. The aim of the
study was to find by in vivo 31 P MRS suitable markers of early stages of brain degeneration …

Hypotensive and neurometabolic effects of intragastric Reishi (Ganoderma lucidum) administration in hypertensive ISIAH rat strain

OB Shevelev, AA Seryapina, EL Zavjalov… - Phytomedicine, 2018 - Elsevier
Background As the standard clinically used hypotensive medicines have many undesirable
side effects, there is a need for new therapeutic agents, especially ones of a natural origin …

Huperzine aggravated neurochemical and volumetric changes induced by D-galactose in the model of neurodegeneration in rats

L Melichercik, T Tvrdik, K Novakova, M Nemec… - Neurochemistry …, 2022 - Elsevier
The multimodal MRI and 1 H MRS study was designed to provide a structural and
neurochemical view of D-galactose induced rat brain degeneration and its treatment with …

[HTML][HTML] Simvastatin ameliorates cognitive impairments via inhibition of oxidative stress‑induced apoptosis of hippocampal cells through the ERK/AKT signaling …

W Liu, Y Zhao, X Zhang, J Ji - Molecular Medicine …, 2018 - spandidos-publications.com
Senile dementia is a degenerative disease of the nervous system associated with cognitive
impairments, memory disorders, executive dysfunctions, cognitive decline and dementia …

Simvastatin-loaded nanoemulsions: Development, characterization, stability study and toxicity assays

MP Moreira, RG Budel, J Wergutz… - Therapeutic …, 2020 - Taylor & Francis
Aim: The aim of this study is to prepare and characterize simvastatin-loaded nanoemulsions
(SIM-LN) as well as evaluate their physicochemical properties and toxicity. Methodology & …

Effects of a compound from the group of substituted thiadiazines with hypothermia inducing properties on brain metabolism in rats, a study in vivo and in vitro

OB Shevelev, NB Illarionova, DV Petrovski… - PloS one, 2017 - journals.plos.org
The aim of the present study was to examine how administration of a compound of 1, 3, 4-
thiadiazine class 2-morpholino-5-phenyl-6H-1, 3, 4-thiadiazine, hydrobromide (L-17) with …

Brain metabolites in ISIAH and Wistar rats

OB Shevelev, AA Seryapina, AL Markel… - Russian Journal of …, 2016 - Springer
Hypertension is one of the most common human diseases, which leads to serious
disturbances, such as myocardial infarction and stroke. A decrease in the neuron viability in …

Mетаболиты мозга у крыс линий НИСАГ и Вистар

ОБ Шевелев, АА Серяпина, АЛ Маркель… - … журнал генетики и …, 2015 - vavilov.elpub.ru
Аннотация Гипертоническая болезнь относится к одному из наиболее
распространенных заболеваний человека. Эта болезнь приводит к таким серьезным …

[PDF][PDF] Brain metabolites in ISIAH and Wistar rats

ОБ Шевелев, АА Серяпина, АЛ Маркель, МП Мошкин - 2015 - sites.icgbio.ru
Hypertension is one of the most common human diseases. This disease leads to serious
disturbances such as myocardial infarction and stroke. Due to the development of nuclear …