The cross‐linking approach combined with MS for protein structure determination is one of
the most striking examples of multidisciplinary success. Indeed, it has become clear that the …

After more than a decade of method development, cross-linking in combination with mass
spectrometry and bioinformatics is finally coming of age. This technology now provides …

A modular assembly of water-soluble diarylethenes (DAEs), applicable as biomarkers for
optical nanoscopy, is reported. Reversibly photoswitchable 1, 2-bis (2-alkyl-6-phenyl-1 …

A newcomer to the-omics era, proteomics, is a broad instrument-intensive research area that
has advanced rapidly since its inception less than 20 years ago. Although the 'wet …

Abstract Reversibly photoswitchable 1, 2‐bis (2‐ethyl‐6‐phenyl‐1‐benzothiophene‐1, 1‐
dioxide‐3‐yl) perfluorocyclopentenes (EBT) having fluorescent “closed” forms were …

Structural proteomics is the application of protein chemistry and modern mass spectrometric
techniques to problems such as the characterization of protein structures and assemblies …

The fungal natural product aspergillomarasmine A (AMA) has been identified as a
noncompetitive inhibitor of New Delhi metallo‐β‐lactamase‐1 (NDM‐1) that inhibits by …

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has been
demonstrated to be a valuable tool to investigate noncovalent interactions of biomolecules …

Chemical probing represents a very versatile alternative for studying the structure and
dynamics of substrates that are intractable by established high‐resolution techniques. The …

Understanding the way how proteins interact with each other to form transient or stable
protein complexes is a key aspect in structural biology. In this study, we combined chemical …