Due to their ultra-small size, nanoparticles (NPs) have distinct properties compared with the
bulk form of the same materials. These properties are rapidly revolutionizing many areas of …

Amyloidosis is a heterogeneous group of diseases with a common feature of extracellular
deposition and infiltration of different types of amyloid fibrils in various organs. For example …

Nanoscale materials have been envisioned as carriers for various therapeutic drugs,
including radioisotopes. Inorganic nanoparticles (NPs) are particularly appealing vehicles …

The monoclonal antibody 2A4 binds an epitope derived from a cleavage site of serum
amyloid protein A (sAA) containing a-Glu-Asp-amino acid pairing. In addition to its reactivity …

Herein we characterize an apparently balanced de novo translocation, t (X; 15)(p22. 2; q26.
1) dn, in a female patient with scoliosis, hirsutism, learning problems, and developmental …

Heparan sulfate proteoglycans (HSPGs) are ubiquitous components of pathologic amyloid
deposits in the organs of patients with disorders such as Alzheimer's disease or systemic …

Heparan sulfate (HS) is a structurally complex polysaccharide that interacts with a broad
spectrum of extracellular effector ligands and thereby is thought to regulate a diverse array …

Amyloid is a complex pathologic matrix comprised principally of paracrystalline protein fibrils
and heparan sulfate proteoglycans. Systemic amyloid diseases are rare, thus, routine …

Serum amyloid P component (SAP) binds to amyloid. 123I-SAP scintigraphy is used to
evaluate the extent and distribution of amyloid in systemic amyloidosis and has great clinical …

Objective: AA amyloidosis is a complication to longstanding inflammatory diseases, but
reduction of amyloid mass has been reported as the inflammation ceases. Not much is …