A review: FDA-approved fluorine-containing small molecules from 2015 to 2022
N Sheikhi, M Bahraminejad, M Saeedi… - European Journal of …, 2023 - Elsevier
Fluorine-containing small molecules have occupied an especial position in drug discovery
research. The successful clinical use of fluorinated corticosteroids in the 1950s and …
research. The successful clinical use of fluorinated corticosteroids in the 1950s and …
20 years since the approval of first EGFR-TKI, gefitinib: Insight and foresight
S Singh, S Sadhukhan, A Sonawane - Biochimica et Biophysica Acta (BBA) …, 2023 - Elsevier
Epidermal growth factor receptor (EGFR) actively involves in modulation of various cancer
progression related mechanisms including angiogenesis, differentiation and migration …
progression related mechanisms including angiogenesis, differentiation and migration …
Combination of betulinic acid and EGFR-TKIs exerts synergistic anti-tumor effects against wild-type EGFR NSCLC by inducing autophagy-related cell death via EGFR …
H Wang, X Du, W Liu, C Zhang, Y Li, J Hou, Y Yu… - Respiratory …, 2024 - Springer
Background Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have
revolutionized the treatment of lung cancer patients with mutated EGFR. However, the …
revolutionized the treatment of lung cancer patients with mutated EGFR. However, the …
[PDF][PDF] The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers
RS Iyer, SR Needham, I Galdadas, BM Davis… - bioRxiv, 2023 - academia.edu
Epidermal growth factor receptor (EGFR) is central to cell growth in physiology and
pathophysiologies, including non-small cell lung cancer (NSCLC). EGFR has been …
pathophysiologies, including non-small cell lung cancer (NSCLC). EGFR has been …
The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound mechanisms assembling ligand-free EGFR oligomer structures
RS Iyer, SR Needham, I Galdadas, BM Davis… - bioRxiv, 2023 - biorxiv.org
Epidermal growth factor receptor (EGFR) is central to cell growth in physiology and
pathophysiologies, including non-small cell lung cancer (NSCLC). EGFR has been …
pathophysiologies, including non-small cell lung cancer (NSCLC). EGFR has been …