Biological effects of gyrophoric acid and other lichen derived metabolites, on cell proliferation, apoptosis and cell signaling pathways

M Mohammadi, L Bagheri, A Badreldin, P Fatehi… - Chemico-biological …, 2022 - Elsevier
Secondary metabolites from fungi, algae and lichens have remarkable biological activities
as antibiotics, fungicides, antiviral drugs, and cancer therapeutics. This review focuses on …

Lichens: A promising source of anti-cancerous activity and their molecular mechanisms

M Thakur, B Kapoor, D Kapoor, NR Sharma - South African Journal of …, 2023 - Elsevier
The potential of lichens for medicinal use is to have a variety of bioactive anticancer
compounds. Several factors drive the issue of lichens as a usual substance of carcinoma …

In Silico Pharmacokinetic Profiling of the Identified Bioactive Metabolites of Pergularia tomentosa L. Latex Extract and In Vitro Cytotoxic Activity via the Induction of …

AS Abouzied, MM Abd-Rabo, B Huwaimel… - Pharmaceuticals, 2022 - mdpi.com
The in vitro cytotoxic efficacy of plant latex from Pergularia tomentosa L. was studied using
five human cancer cell lines: HeLa cells (cervical carcinoma cells), A-549 (lung carcinoma) …

Inhibition of autophagy increases cell death in HeLa cells through usnic acid isolated from lichens

M Kumari, S Kamat, SK Singh, A Kumar… - Plants, 2023 - mdpi.com
The Western Ghats, India, is a hotspot for lichen diversity. However, the pharmacological
importance of lichen-associated metabolites remains untapped. This study aimed to …

Xerophytic Lichens from Gypsiferous Outcrops of Arid Areas of Andalusia as a Source of Anti-Phytopathogenic Depsides

I Fernández-Pastor, V González-Menéndez… - Journal of Fungi, 2023 - mdpi.com
In a survey to evaluate the potential of lichens associated with gypsum areas as sources of
new antifungal metabolites, six species of lichens were collected in the gypsum outcrops of …

Isolation of Antibacterial Depside Constituents from Indonesian Folious Lichen, Candelaria fibrosa

AS Nugraha, IR Dayli, CPZ Sukrisno Putri… - Journal of Biologically …, 2022 - Taylor & Francis
There is an urgent need for novel drug leads, especially for microbial infections due to
continuing emergence of drug resistance. Natural products are the backbone of modern …

[PDF][PDF] Pharmacological activities and potential use of bovine colostrum for peptide-based radiopharmaceuticals: A review

CE Kusumaningrum, EM Widyasari, ME Sriyani… - …, 2021 - pharmacia.pensoft.net
Bovine colostrum (BC) is the initial milk produced by cows after giving birth. It has been used
to treat human diseases, such as infections, inflammations, and cancers. Accumulating …

Lichens: A Source of Anticancer Drugs

AS Nugraha, THY Lam, H Wongso… - Chemistry, Biology …, 2024 - Wiley Online Library
Lichen species have been one of the interesting organisms in bioprospecting for new
anticancer agents. More than 18,500 lichens have been identified for their taxonomical …

Exploring the role of fluorescence image-guided surgery (FIGS) in surgical oncology (nuclear medicine)

H Wongso, I Mahendra, A Kurniawan - AIP Conference Proceedings, 2021 - pubs.aip.org
Surgical resection, in combination with or without chemotherapy/radiotherapy remains the
primary treatment option for cancer patients. The main goal of surgery is to achieve complete …

The metabolite 5-methyl-1,3-benzenediol and its derivative methyl-2,4-dihydroxy-6-methylbenzoate from the lichen Parmotrema tinctorum with potent apoptotic and …

A Bhaktavalsala Suresh, V Kilingar Nadumane - 3 Biotech, 2021 - Springer
Nature has been a rich resource of novel anticancer agents, one such source being lichens,
which represent the symbiosis between algae and fungi with diverse range of secondary …