Introduction: Prediction of neurodevelopmental outcome in infants with hypoxic-ischemic
encephalopathy remains an important challenge. Various studies have shown that the …

Background Heterogeneity in outcomes reported in trials of interventions for the treatment of
neonatal encephalopathy (NE) makes evaluating the effectiveness of treatments difficult …

Background Deep nuclear gray matter injury in neonatal hypoxic-ischemic encephalopathy
(HIE) is associated with worse neurodevelopmental outcomes. We previously published a …

Impaired cerebral autoregulation may contribute to secondary injury in newborns with
hypoxic-ischemic encephalopathy (HIE). Continuous, noninvasive assessment of cerebral …

Background The aim of this study was to ascertain risks of neonatal mortality, severe
neurological morbidity and severe non-neurological morbidity related to the 5-min Apgar …

Interleukin-1 (IL-1) is a potent inflammatory cytokine that can be produced by a variety of cell
types throughout the body. While IL-1 is a central mediator of inflammation and response to …

Neonatal brain injury or neonatal encephalopathy (NE) is a significant morbidity and
mortality factor in preterm and full-term newborns. NE has an incidence in the range of 2.5 to …

The embryo and fetus grow in a hypoxic environment. Intrauterine oxygen levels fluctuate
throughout the pregnancy, allowing the oxygen to modulate apparently contradictory …

Background The cerebroplacental ratio is associated with perinatal mortality and morbidity,
but it is unknown whether routine measurement improves pregnancy outcomes. We aimed …

The objective was to examine the discriminatory ability of electroencephalogram (EEG) delta
power in neonates with hypoxic-ischemic encephalopathy (HIE) with well-defined outcomes …