Hepatocellular carcinoma (HCC) is a common malignancy threatening human health, and existing diagnostic and therapeutic techniques are facing great challenges. In the last …
A new positively charged nanoemulsion using quaternized chitosan (QCS) as a protective layer was developed to improve the stability and bioactivity of lipophilic active components …
J Li, W Zhou, Q Mao, D Gao, L Xiong, X Hu… - Frontiers in …, 2021 - frontiersin.org
Chemoresistance remains as a major hindrance in the treatment of hepatocellular carcinoma (HCC). High mobility group box protein 1 (HMGB1) enhances autophagic flux …
Fisetin is a plant derived flavonoid that possesses anti-cancer, anti-oxidant and anti- Parkinson's activities. However, due to its lipophilicity it suffers from dissolution rate limited …
This current study aims to optimize, characterize, and observe the stability of the self-nano emulsifying drug delivery system (SNEDDS) of propolis extract (PE) for improving the …
Gastric ulcer is a common gastrointestinal ailment that affects many people worldwide. NSAIDs induced ulcers are the second most common etiology of gastric ulcers. Coconut oil …
TA Ahmed, HA Alotaibi, WS Alharbi, MK Safo… - Pharmaceuticals, 2022 - mdpi.com
Glimepiride is characterized by an inconsistent dissolution and absorption profile due to its limited aqueous solubility. The aim of this study was to develop glimepiride tablets using …
The research work was designed to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox (DFX). According to the solubility studies of DFX in …
RA Saeed, M Maqsood, RA Saeed… - Critical Reviews in …, 2023 - Taylor & Francis
Regardless of etiology, hepatocarcinogenesis is frequently preceded by a distinctive sequence of chronic necroinflammation, compensatory hepatic regeneration, development …