Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

K Mahmoud, S Swidan, M El-Nabarawi… - Journal of …, 2022 - Springer
Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

Nanotechnology strategies for hepatocellular carcinoma diagnosis and treatment

WL Jia, YH Han, XY Mao, WJ Xu, YW Zhang - RSC advances, 2022 - pubs.rsc.org
Hepatocellular carcinoma (HCC) is a common malignancy threatening human health, and
existing diagnostic and therapeutic techniques are facing great challenges. In the last …

Quaternized chitosan-coated nanoemulsions: A novel platform for improving the stability, anti-inflammatory, anti-cancer and transdermal properties of Plai extract

U Luesakul, S Puthong, K Sansanaphongpricha… - Carbohydrate …, 2020 - Elsevier
A new positively charged nanoemulsion using quaternized chitosan (QCS) as a protective
layer was developed to improve the stability and bioactivity of lipophilic active components …

HMGB1 Promotes Resistance to Doxorubicin in Human Hepatocellular Carcinoma Cells by Inducing Autophagy via the AMPK/mTOR Signaling Pathway

J Li, W Zhou, Q Mao, D Gao, L Xiong, X Hu… - Frontiers in …, 2021 - frontiersin.org
Chemoresistance remains as a major hindrance in the treatment of hepatocellular
carcinoma (HCC). High mobility group box protein 1 (HMGB1) enhances autophagic flux …

Self-nanoemulsifying drug delivery system of fisetin: Formulation, optimization, characterization and cytotoxicity assessment

R Kumar, R Khursheed, R Kumar, A Awasthi… - Journal of drug delivery …, 2019 - Elsevier
Fisetin is a plant derived flavonoid that possesses anti-cancer, anti-oxidant and anti-
Parkinson's activities. However, due to its lipophilicity it suffers from dissolution rate limited …

[HTML][HTML] Design and characterization of propolis extract loaded self-nano emulsifying drug delivery system as immunostimulant

A Fitria, S Hanifah, L Chabib, AM Uno… - Saudi Pharmaceutical …, 2021 - Elsevier
This current study aims to optimize, characterize, and observe the stability of the self-nano
emulsifying drug delivery system (SNEDDS) of propolis extract (PE) for improving the …

Coconut oil based self-nano emulsifying delivery systems mitigate ulcerogenic NSAIDs side effect and enhance drug dissolution: Formula optimization, in-vitro, and in …

SM Fayez, OS Elnahas, AM Fayez… - International Journal of …, 2023 - Elsevier
Gastric ulcer is a common gastrointestinal ailment that affects many people worldwide.
NSAIDs induced ulcers are the second most common etiology of gastric ulcers. Coconut oil …

Development of 3D-printed, liquisolid and directly compressed glimepiride tablets, loaded with black seed oil self-nanoemulsifying drug delivery system: in vitro and in …

TA Ahmed, HA Alotaibi, WS Alharbi, MK Safo… - Pharmaceuticals, 2022 - mdpi.com
Glimepiride is characterized by an inconsistent dissolution and absorption profile due to its
limited aqueous solubility. The aim of this study was to develop glimepiride tablets using …

A solid ultra fine self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox for improved solubility: optimization, characterization, and in vitro cytotoxicity …

A Alghananim, Y Özalp, B Mesut, N Serakinci, Y Özsoy… - Pharmaceuticals, 2020 - mdpi.com
The research work was designed to develop a solid self-nanoemulsifying drug delivery
system (S-SNEDDS) of deferasirox (DFX). According to the solubility studies of DFX in …

Plant-based foods and hepatocellular carcinoma: A review on mechanistic understanding

RA Saeed, M Maqsood, RA Saeed… - Critical Reviews in …, 2023 - Taylor & Francis
Regardless of etiology, hepatocarcinogenesis is frequently preceded by a distinctive
sequence of chronic necroinflammation, compensatory hepatic regeneration, development …