We propose and empirically support a parsimonious account of intrinsic, brain-wide
spatiotemporal organization arising from traveling waves linked to arousal. We hypothesize …

Sleep is ubiquitous and essential, but its mechanisms remain unclear. Studies in animals
and humans have provided insights of sleep at vastly different spatiotemporal scales …

To understand how arousal state impacts cerebral hemodynamics and neurovascular
coupling, we monitored neural activity, behavior, and hemodynamic signals in un …

The glymphatic system plays an important role in clearing the amyloid-β (Aβ) and tau
proteins that are closely linked to Alzheimer disease (AD) pathology. Glymphatic clearance …

How global and local activity interact with each other is a common question in complex
systems like climate and economy. Analogously, the brain too displays 'global'activity that …

Resting-state functional magnetic resonance imaging (rsfMRI) allows the study of functional
brain connectivity based on spatially structured variations in neuronal activity. Proper …

Correlated fluctuations in the blood oxygenation level dependent (BOLD) signal of resting-
state functional MRI (ie, BOLD-functional connectivity, BOLD-FC) reflect a spectrum of …

Falling asleep is common in fMRI studies. By using long eyelid closures to detect microsleep
onset, we showed that the onset and termination of short sleep episodes invokes a …

During normal aging, the brain undergoes structural and functional changes. Many studies
applied static functional connectivity (FC) analysis on resting state functional magnetic …

Neural activity in awake organisms shows widespread and spatiotemporally diverse
correlations with behavioral and physiological measurements. We propose that this …