The enzymology of organic transformations: a survey of name reactions in biological systems
Chemical reactions that are named in honor of their true, or at least perceived, discoverers
are known as “name reactions”. This Review is a collection of biological representatives of …
are known as “name reactions”. This Review is a collection of biological representatives of …
Isolation and characterization of lytic phage vB_EcoM_JS09 against clinically isolated antibiotic-resistant avian pathogenic Escherichia coli and enterotoxigenic …
Y Zhou, H Bao, H Zhang, R Wang - Intervirology, 2015 - karger.com
Objectives: To characterize the lytic coliphage vB_EcoM_JS09 (phage JS09) isolated from
sewage samples of a swine farm in Jiangsu Province, China, which infects antibiotic …
sewage samples of a swine farm in Jiangsu Province, China, which infects antibiotic …
Prediction of Active Site and Distal Residues in E. coli DNA Polymerase III alpha Polymerase Activity
R Parasuram, TA Coulther, JM Hollander… - Biochemistry, 2018 - ACS Publications
The process of DNA replication is carried out with high efficiency and accuracy by DNA
polymerases. The replicative polymerase in E. coli is DNA Pol III, which is a complex of 10 …
polymerases. The replicative polymerase in E. coli is DNA Pol III, which is a complex of 10 …
Molecular events during translocation and proofreading extracted from 200 static structures of DNA polymerase
Z Ren - Nucleic acids research, 2016 - academic.oup.com
DNA polymerases in family B are workhorses of DNA replication that carry out the bulk of the
job at a high speed with high accuracy. A polymerase in this family relies on a built-in …
job at a high speed with high accuracy. A polymerase in this family relies on a built-in …
Direct observation of nanosecond water exchange dynamics at a protein metal site
M Stachura, S Chakraborty, A Gottberg… - Journal of the …, 2017 - ACS Publications
Nanosecond ligand exchange dynamics at metal sites within proteins is essential in
catalysis, metal ion transport, and regulatory metallobiochemistry. Herein we present direct …
catalysis, metal ion transport, and regulatory metallobiochemistry. Herein we present direct …
Remote mutations induce functional changes in active site residues of human DNA polymerase β
BE Eckenroth, JB Towle-Weicksel, AA Nemec… - Biochemistry, 2017 - ACS Publications
With the formidable growth in the volume of genetic information, it has become essential to
identify and characterize mutations in macromolecules not only to predict contributions to …
identify and characterize mutations in macromolecules not only to predict contributions to …
Die Enzymologie organischer Umwandlungen: Namensreaktionen in biologischen Systemen
Abstract Chemische Reaktionen, die zu Ehren ihrer wahren oder zumindest
wahrgenommenen Entdecker benannt sind, werden als “Namensreaktionen” bezeichnet …
wahrgenommenen Entdecker benannt sind, werden als “Namensreaktionen” bezeichnet …
Increased processivity, misincorporation, and nucleotide incorporation efficiency in Sulfolobus solfataricus Dpo4 thumb domain mutants
L Wang, C Liang, J Wu, L Liu… - Applied and Environmental …, 2017 - Am Soc Microbiol
The present study aimed to increase the processivity of Sulfolobus solfataricus DNA
polymerase Dpo4. Protein engineering and bioinformatics were used to compile a library of …
polymerase Dpo4. Protein engineering and bioinformatics were used to compile a library of …
[图书][B] Electrostatics-based computational methods for understanding polymerase mechanism and for protein function annotation
R Parasuram - 2014 - search.proquest.com
Abstract Knowledge of the active site is the first step to understanding the function of an
enzyme. My research encompassed the use of electrostatics-based computational functional …
enzyme. My research encompassed the use of electrostatics-based computational functional …