Non-union bone fractures

B Wildemann, A Ignatius, F Leung… - Nature reviews Disease …, 2021 - nature.com
The human skeleton has remarkable regenerative properties, being one of the few
structures in the body that can heal by recreating its normal cellular composition, orientation …

[PDF][PDF] Reverse dynamisation: a modern perspective on Stephan Perren's strain theory

V Glatt, CH Evans, K Tetsworth - Eur Cell Mater, 2021 - academia.edu
The present review acknowledges the tremendous impact of Stephan Perren's strain theory,
considered with respect to the earlier contributions of Roux and Pauwels. Then, it provides …

The absence of immediate stimulation delays bone healing

J Barcik, M Ernst, T Buchholz, C Constant, K Mys… - Bone, 2023 - Elsevier
Aim Secondary bone healing requires an adequate level of mechanical stimulation
expressed by the extent of interfragmentary motion in the fracture. However, there is no …

Reverse dynamization accelerates regenerate bone formation and remodeling in a goat distraction osteogenesis model

A Bafor, C Iobst, M Samchukov, A Cherkashin, S Singh… - JBJS, 2023 - journals.lww.com
Background: The concept of reverse dynamization involves modifying the mechanical
environment surrounding a fracture to influence the healing response. Initially, less rigid …

A PEEK into carbon fiber: A practical guide for high performance composite polymeric implants for orthopaedic oncology

MJ Clunk, MR Gonzalez, HM Denwood… - Journal of …, 2023 - Elsevier
Introduction The use of carbon fiber implants in orthopaedic oncology has increased within
recent years. The most widely used type of polymer is carbon fiber polyether ether ketone …

Long bone defect filling with bioactive degradable 3D-implant: experimental study

A Popkov, N Kononovich, G Dubinenko, E Gorbach… - Biomimetics, 2023 - mdpi.com
Previously, 3D-printed bone grafts made of titanium alloy with bioactive coating has shown
great potential for the restoration of bone defects. Implanted into a medullary canal titanium …

[HTML][HTML] Targeting micromotion for mimicking natural bone healing by using NIPAM/Nb2C hydrogel

Q Yang, M Xu, H Fang, Y Gao, D Zhu, J Wang, Y Chen - Bioactive Materials, 2024 - Elsevier
Natural fracture healing is most efficient when the fine-tuned mechanical force and proper
micromotion are applied. To mimick this micromotion at the fracture gap, a near-infrared-II …

Comparison between external locking plate fixation and conventional external fixation for extraarticular proximal tibial fractures: a finite element analysis

D Blažević, J Kodvanj, P Adamović, D Vidović… - Journal of Orthopaedic …, 2022 - Springer
Background Good clinical outcomes for locking plates as an external fixator to treat tibial
fractures have been reported. However, external locking plate fixation is still generally rarely …

Can optimizing the mechanical environment deliver a clinically significant reduction in fracture healing time?

J Barcik, DR Epari - Biomedicines, 2021 - mdpi.com
The impact of the local mechanical environment in the fracture gap on the bone healing
process has been extensively investigated. Whilst it is widely accepted that mechanical …

A novel one-degree-of-freedom translational partly compliant mechanism with variable motion direction

J Du, X Zhang, H Zhang, B Zhu, W Zhong - Mechanism and Machine …, 2022 - Elsevier
This study presents the design and analysis of a one-degree-of-freedom (DOF) translational
partly compliant mechanism (TPCM) with variable motion direction. The variable motion …