Reproduction is required for the survival of all mammalian species, and thousands of
essential'sex'genes are conserved through evolution. Basic research helps to define these …

Aneuploidy is the most common chromosome abnormality in humans, and is the leading
genetic cause of miscarriage and congenital birth defects. Since the identification of the first …

Proper response of normal stem cells (NSC) to motomorphogens and chemoattractants
plays a pivotal role in organ development and renewal/regeneration of damaged tissues …

The Pou domain containing transcription factor Oct4 is a well-established regulator of
pluripotency in the inner cell mass of the mammalian blastocyst as well as in embryonic …

Stem cells are self-renewing and undifferentiated cell types that can be differentiate into
functional cells. Stem cells can be classified into two main types based on their source of …

Oct4 is a key component of the pluripotency regulatory network, and its reciprocal interaction
with Cdx2 has been shown to be a determinant of either the self-renewal of embryonic stem …

Recently, we purified from adult murine bone marrow (BM) a population of CXCR4+, Oct-4+
SSEA-1+, Sca-1+ lin− CD45− very small embryonic-like (VSEL) stem cells and hypothesized …

The Editor-in-Chief of Stem Cells and Development officially retracts the article
entitled,“Detection, Characterization, and Spontaneous Differentiation In Vitro of Very Small …

Purpose Although early menopause frequently occurs in female cancer patients after
chemotherapy (CTx), bone marrow (BM) transplantation (BMT) has been linked to an …

Mesenchymal stem cells (MSCs) are a very important adult stem cell population with a
multitude of potential applications in regenerative medicine. The thorough characterization …