The dawn of a new era: tumor-targeting boron agents for neutron capture therapy

T Luo, W Huang, F Chu, T Zhu, B Feng… - Molecular …, 2023 - ACS Publications
Cancer is widely recognized as one of the most devastating diseases, necessitating the
development of intelligent diagnostic techniques, targeted treatments, and early prognosis …

Biopolymer-based nanogel approach in drug delivery: basic concept and current developments

E Altuntaş, B Özkan, S Güngör, Y Özsoy - Pharmaceutics, 2023 - mdpi.com
Due to their increased surface area, extent of swelling and active substance-loading
capacity and flexibility, nanogels made from natural and synthetic polymers have gained …

Extracellular Vesicles Comprising Carborane Prepared by a Host Exchanging Reaction as a Boron Carrier for Boron Neutron Capture Therapy

R Kawasaki, A Oshige, N Kono, K Yamana… - … Applied Materials & …, 2024 - ACS Publications
With their low immunogenicity and excellent deliverability, extracellular vesicles (EVs) are
promising platforms for drug delivery systems. In this study, hydrophobic molecule loading …

In Vivo Application of Carboranes for Boron Neutron Capture Therapy (BNCT): Structure, Formulation and Analytical Methods for Detection

TD Marforio, A Carboni, M Calvaresi - Cancers, 2023 - mdpi.com
Simple Summary Boron neutron capture therapy (BNCT) is an emerging anticancer
treatment. The success of BNCT relies on the delivery of adequate quantities of 10B to tumor …

Design and applications of polymer-like peptides in biomedical nanogels

I Neamtu, A Ghilan, AG Rusu, LE Nita… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Polymer nanogels are among the most promising nanoplatforms for use in
biomedical applications. The substantial interest for these drug carriers is to enhance the …

HER-2-targeted boron neutron capture therapy using an antibody-conjugated boron nitride nanotube/β-1, 3-glucan complex

K Yamana, R Kawasaki, K Kondo, H Hirano… - Nanoscale …, 2023 - pubs.rsc.org
The development of boron agents with integrated functionality, including biocompatibility,
high boron content, and cancer cell targeting, is desired to exploit the therapeutic efficacy of …

Exploring the Potential of Nanogels: From Drug Carriers to Radiopharmaceutical Agents

M Kubeil, Y Suzuki, MA Casulli, R Kamal… - Advanced …, 2024 - Wiley Online Library
Nanogels open up access to a wide range of applications and offer among others hopeful
approaches for use in the field of biomedicine. This review provides a brief overview of …

[HTML][HTML] Potential of Pullulan-Based Polymeric Nanoparticles for Improving Drug Physicochemical Properties and Effectiveness

N Thomas, LE Puluhulawa, FR Cindana Mo'o… - Polymers, 2024 - mdpi.com
Pullulan, a natural polysaccharide with unique biocompatibility and biodegradability, has
gained prominence in nanomedicine. Its application in nanoparticle drug delivery systems …

HER‐2‐Targeted Boron Neutron Capture Therapy with Carborane‐integrated Immunoliposomes Prepared via an Exchanging Reaction

R Kawasaki, A Oshige, K Yamana… - … A European Journal, 2023 - Wiley Online Library
Boron neutron capture therapy (BNCT) is a promising modality for cancer treatment because
of its minimal invasiveness. To maximize the therapeutic benefits of BNCT, the development …

[HTML][HTML] Recent progress of nano-drugs in neutron capture therapy

YT Zhou, K Cheng, B Liu, YC Cao, JX Fan, ZG Liu… - Theranostics, 2024 - ncbi.nlm.nih.gov
As a developing radiation treatment for tumors, neutron capture therapy (NCT) has less side
effects and a higher efficacy than conventional radiation therapy. Drugs with specific …