Eukaryotic core promoters and the functional basis of transcription initiation
Abstract RNA polymerase II (Pol II) core promoters are specialized DNA sequences at
transcription start sites of protein-coding and non-coding genes that support the assembly of …
transcription start sites of protein-coding and non-coding genes that support the assembly of …
The RNA polymerase II core promoter
ST Smale, JT Kadonaga - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract The events leading to transcription of eukaryotic protein-coding genes culminate
in the positioning of RNA polymerase II at the correct initiation site. The core promoter, which …
in the positioning of RNA polymerase II at the correct initiation site. The core promoter, which …
Transcription of eukaryotic protein-coding genes
TI Lee, RA Young - Annual review of genetics, 2000 - annualreviews.org
▪ Abstract The past decade has seen an explosive increase in information about regulation
of eukaryotic gene transcription, especially for protein-coding genes. The most striking …
of eukaryotic gene transcription, especially for protein-coding genes. The most striking …
[HTML][HTML] Identification and distinct regulation of yeast TATA box-containing genes
AD Basehoar, SJ Zanton, BF Pugh - Cell, 2004 - cell.com
Despite being one of the first eukaryotic transcriptional regulatory elements identified, the
sequence of a native TATA box and its significance remain elusive. Applying criteria …
sequence of a native TATA box and its significance remain elusive. Applying criteria …
Crystal structure of a yeast TBP/TATA-box complex
The 2.5 Å crystal structure of a TATA-box complex with yeast TBP shows that the eight base
pairs of the TATA box bind to the concave surface of TBP by bending towards the major …
pairs of the TATA box bind to the concave surface of TBP by bending towards the major …
Co-crystal structure of TBP recognizing the minor groove of a TATA element
JL Kim, DB Nikolov, SK Burley - Nature, 1993 - nature.com
The three-dimensional structure of a TATA-box binding polypeptide complexed with the
TATA element of the adenovirus major late promoter has been determined by X-ray …
TATA element of the adenovirus major late promoter has been determined by X-ray …
Molecular genetics of the RNA polymerase II general transcriptional machinery
M Hampsey - Microbiology and Molecular Biology Reviews, 1998 - Am Soc Microbiol
Transcription initiation by RNA polymerase II (RNA pol II) requires interaction between cis-
acting promoter elements and trans-acting factors. The eukaryotic promoter consists of core …
acting promoter elements and trans-acting factors. The eukaryotic promoter consists of core …
Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters
The core promoter of eukaryotic genes is the minimal DNA region that recruits the basal
transcription machinery to direct efficient and accurate transcription initiation. The fraction of …
transcription machinery to direct efficient and accurate transcription initiation. The fraction of …
Facilitated binding of TATA-binding protein to nucleosomal DNA
AN Imbalzano, H Kwon, MR Green, RE Kingston - Nature, 1994 - nature.com
BINDING of the TATA-binding protein (TBP) to the TATA box is required for transcription from
many eukaryotic promoters in gene expression. Regulation of this binding is therefore likely …
many eukaryotic promoters in gene expression. Regulation of this binding is therefore likely …
Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway
GH Braus - Microbiological reviews, 1991 - Am Soc Microbiol
This review focuses on the gene-enzyme relationships and the regulation of different levels
of the aromatic amino acid biosynthetic pathway in a simple eukaryotic system, the …
of the aromatic amino acid biosynthetic pathway in a simple eukaryotic system, the …