Metabolic phenotyping is an important tool in translational biomedical research. The
advanced analytical technologies commonly used for phenotyping, including mass …

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI)
disorders. Determining its mechanistic role in disease has been difficult due to apparent …

The human microbiome and its metabolic output play an important role in shaping human
health and disease. The host-microbe crosstalk is often characterised using metabolomics …

Metabolic profiling of biological samples provides important insights into multiple
physiological and pathological processes but is hindered by a lack of automated annotation …

ABSTRACT Background Alaska Native (AN) people have the world's highest recorded
incidence of sporadic colorectal cancer (CRC)(∼ 91: 100,000), whereas rural African (RA) …

Abstract Proton Nuclear Magnetic Resonance (NMR) spectroscopic analysis of urine
generates rich but complex spectra. Retrieving metabolite information from such spectra is …

Dietary assessment traditionally relies on self-reported data, which are often inaccurate and
may result in erroneous diet–disease risk associations. We illustrate how urinary metabolic …

Methotrexate (MTX) is a chemotherapeutic agent that can cause a range of toxic side effects
including gastrointestinal damage, hepatotoxicity, myelosuppression, and nephrotoxicity …

Background and aims The gut microbiota is implicated in the pathogenesis of colorectal
cancer (CRC). We aimed to map the CRC mucosal microbiota and metabolome and define …

An understanding of the metabolic determinants of postexercise appetite regulation would
facilitate development of adjunctive therapeutics to suppress compensatory eating …