Passive mechanical tissue properties are major determinants of myocardial contraction and
relaxation and, thus, shape cardiac function. Tightly regulated, dynamically adapting …

The structural-functional hallmark of the liver sinusoidal endothelium is the presence of
fenestrae grouped in sieve plates. Fenestrae are open membrane bound pores supported …

Background Liver sinusoidal endothelial cells (LSECs) have transcellular pores, called
fenestrations, participating in the bidirectional transport between the vascular system and …

Atomic force microscopy (AFM) is widely used for quantifying the mechanical properties of
soft materials such as cells. AFM force-indentation curves are conventionally fitted with a …

Vascular stiffness is an independent predictor of human vascular diseases and is linked to
ischemia, diabetes, high blood pressure, hyperlipidemia, and/or aging. Blood vessel …

In recent years, atomic force spectroscopy (AFS) has been used to detect and characterize
the endothelial glycocalyx (eGlx) in in vitro and ex vivo experiments. Several analysis …

The mechanical behaviour of adherent cells when subjected to the local indentation can be
modelled via various approaches. Specifically, the tensegrity structure has been widely used …

Triple negative breast cancer (TNBC) is one of the most aggressive breast cancer subtype
and with a poor prognosis. Nowadays, chemotherapy is the main treatment in both early and …