Sickle cell disease is an autosomal recessive disorder of the beta-globin gene, with resultant
deformation of the red blood cells and variable clinical outcomes. Nigeria is recognised as …

Background Effective treatment and management of sickle cell disease (SCD) has been a
challenge in Africa over the years. Hematological parameters are very useful profiles in the …

Background Sickle cell anemia (SCA) is a severe monogenic disorder, caused by single
nucleotide mutations in the hemoglobin (Hb) gene, that is prevalent in malaria endemic …

Introduction: nutritional status is an under-studied environmental factor that can impact the
phenotypic manifestations of patients with Sickle cell anaemia (SCA). This study aimed to …

Background: Sickle cell anemia (SCA) is the most common and severest form of sickle cell
disease. It affects about 3% of the Nigerian population with a high mortality in children …

Hematological and biochemical reference values in sickle cell disease (SCD) are crucial for
patient management and the evaluation of interventions. This study was conducted at …

In view of the association of various haemoglobin electrophoretic patterns with different
pathological conditions and obesity with its attendant risk factors for cardiac and pulmonary …

Methods A retrospective review of clinical files of children with SCD was conducted.
Descriptive statistics were performed to summarise the data. χ 2 or Fisher's exact test was …

Background The aim of this study was to determine the prevalence of invasive bacterial
infections and their antimicrobial resistance patterns in sickle cell disease (SCD) patients …

BACKGROUND: Platelet parameters in steady-state sickle cell anemia (SCA) are affected by
the red cell sickling, vaso-occlusion, and chronic hemolysis occasioned by the disease; and …