Hydrogel interfaces for merging humans and machines

H Yuk, J Wu, X Zhao - Nature Reviews Materials, 2022 - nature.com
The last few decades have witnessed unprecedented convergence between humans and
machines that closely operate around the human body. Despite these advances, traditional …

The fast-growing field of photo-driven theranostics based on aggregation-induced emission

Z Zhang, M Kang, H Tan, N Song, M Li, P Xiao… - Chemical Society …, 2022 - pubs.rsc.org
Photo-driven theranostics, also known as phototheranostics, relying on the diverse excited-
state energy conversions of theranostic agents upon photoexcitation represents a significant …

To PEGylate or not to PEGylate: Immunological properties of nanomedicine's most popular component, polyethylene glycol and its alternatives

D Shi, D Beasock, A Fessler, J Szebeni… - Advanced drug delivery …, 2022 - Elsevier
Polyethylene glycol or PEG has a long history of use in medicine. Many conventional
formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J Xiang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration

H Wei, J Cui, K Lin, J Xie, X Wang - Bone research, 2022 - nature.com
Bone defects combined with tumors, infections, or other bone diseases are challenging in
clinical practice. Autologous and allogeneic grafts are two main traditional remedies, but …

Dynamic and reconfigurable materials from reversible network interactions

MJ Webber, MW Tibbitt - Nature Reviews Materials, 2022 - nature.com
Polymer materials provide solutions to some of the most pressing environmental,
manufacturing and health-care challenges. Traditional thermoplastic and thermoset …

Bioengineered nanogels for cancer immunotherapy

X Ma, SJ Li, Y Liu, T Zhang, P Xue, Y Kang… - Chemical Society …, 2022 - pubs.rsc.org
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Designing bioresponsive nanomaterials for intracellular self-assembly

S Chagri, DYW Ng, T Weil - Nature Reviews Chemistry, 2022 - nature.com
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …

3D-printed microrobots from design to translation

SR Dabbagh, MR Sarabi, MT Birtek, S Seyfi… - Nature …, 2022 - nature.com
Microrobots have attracted the attention of scientists owing to their unique features to
accomplish tasks in hard-to-reach sites in the human body. Microrobots can be precisely …

Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …