Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …

The functional role of cytochrome P450 (CYP) enzymes in the brain is an exciting and
evolving field of research. CYPs are present and active in the brain, with heterogeneous …

Oxygen supplementation is regularly prescribed to patients to treat or prevent hypoxia.
However, excess oxygenation can lead to reduced cerebral blood flow (CBF) in healthy …

Major depressive disorders (MDDs) are often associated with a deficiency in long-chain
omega-3 polyunsaturated fatty acids (ω-3 PUFAs), as well as signs of low-grade …

20-HETE is a potent vasoconstrictor that is implicated in the regulation of blood pressure,
cerebral blood flow and neuronal death following ischemia. Numerous human genetic …

Autofluorescence emission of liver tissue depends on the presence of endogenous
biomolecules able to fluoresce under suitable light excitation. Overall autofluorescence …

The accumulation of extracellular amyloid-β (Aβ) and intracellular hyperphosphorylated τ
proteins in the brain are the hallmarks of Alzheimer's disease (AD). Much of the research …

The cytochrome P450 (CYP) ω-hydroxylases are a subfamily of CYP enzymes. While CYPs
are the main metabolic enzymes that mediate the oxidation reactions of many endogenous …

20-Hydroxyeicosatetraenoic acid (20-HETE) has been shown to positively correlate with
body mass index, hyperglycemia, and plasma insulin levels. This study seeks to identify a …

Essential hypertension (EH) is a leading cause of cardiovascular morbidity and mortality.
Fructus Tribuli (FT), as a traditional medicine, has been frequently used for thousands of …