The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

There is accumulating evidence indicating that aldehyde dehydrogenase (ALDH) activity
selects for cancer cells with increased aggressiveness, capacity for sustained proliferation …

Patients with cancer can go though many stages in their disease, including diagnosis,
recurrence, metastasis, and treatment failure. Cancer stem cells (CSCs) are a subgroup of …

The attempts to identify, isolate and characterize cancer stem cell populations are mostly
dependent on cell-surface markers. In breast cancer, several putative breast cancer stem …

Abstract Background Aldehyde dehydrogenase 1 (ALDH1) is widely used as a specific
cancer stem cell marker in a variety of cancers, and may become a promising target for …

A significant number of discrepancies exist within the literature regarding ALDEFLUOR-
positive stem cell populations in cell lines. We hypothesized that these inconsistencies …

Aims Aldehyde dehydrogenase family 1 member A1 (ALDH1A1) is a putative marker of
breast cancer stem cells (CSCs) with prognostic implications when expressed in cancer or …

Metastasis frequently targets bones, where cancer cells from the primary tumour migrate to
the bone marrow, initiating new tumour growth. Not only is bone the most common site for …

In many types of tumors, especially breast tumors, aldehyde dehydrogenase (ALDH) activity
has been used to identify cancer stem-like cells within the tumor. The presence and quantity …

Background: Aldehyde dehydrogenase-1 (ALDH1) has been shown to be a potential cancer
stem cell marker in different types of cancer. However, the role of its expression in tumor …